Computational methods for gene regulatory networks reconstruction and analysis: a review
FM Delgado, F Gómez-Vela - Artificial intelligence in medicine, 2019 - Elsevier
In the recent years, the vast amount of genetic information generated by new-generation
approaches, have led to the need of new data handling methods. The integrative analysis of …
approaches, have led to the need of new data handling methods. The integrative analysis of …
How to deal with parameters for whole-cell modelling
AC Babtie, MPH Stumpf - Journal of The Royal Society …, 2017 - royalsocietypublishing.org
Dynamical systems describing whole cells are on the verge of becoming a reality. But as
models of reality, they are only useful if we have realistic parameters for the molecular …
models of reality, they are only useful if we have realistic parameters for the molecular …
Mechanistic systems modeling to improve understanding and prediction of cardiotoxicity caused by targeted cancer therapeutics
JV Shim, B Chun, JGC Van Hasselt… - Frontiers in …, 2017 - frontiersin.org
Tyrosine kinase inhibitors (TKIs) are highly potent cancer therapeutics that have been linked
with serious cardiotoxicity, including left ventricular dysfunction, heart failure, and QT …
with serious cardiotoxicity, including left ventricular dysfunction, heart failure, and QT …
The phenotype paradox: lessons from natural transcriptome evolution on how to engineer plants
J Law, K Ng, OPF Windram - Frontiers in Plant Science, 2020 - frontiersin.org
Plants have evolved genome complexity through iterative rounds of single gene and whole
genome duplication. This has led to substantial expansion in transcription factor numbers …
genome duplication. This has led to substantial expansion in transcription factor numbers …
Plasticity of fibroblast transcriptional response to physical and biochemical cues revealed by dynamic network analysis
Data on human skin fibroblast transcriptional responses to external cues were used to
reconstruct dynamic gene regulatory networks. The goal of the reconstruction was to …
reconstruct dynamic gene regulatory networks. The goal of the reconstruction was to …
[PDF][PDF] Lead Contact Pilhwa Lee
P Lee - scholar.archive.org
Data on human skin fibroblast transcriptional responses to external cues were used to
reconstruct dynamic gene regulatory networks. The goal of the reconstruction was to …
reconstruct dynamic gene regulatory networks. The goal of the reconstruction was to …