Agomelatine for the treatment of generalized anxiety disorder: focus on its distinctive mechanism of action

MJ Millan - Therapeutic Advances in Psychopharmacology, 2022 - journals.sagepub.com
Generalized anxiety disorder (GAD), the most frequently diagnosed form of anxiety, is
usually treated by cognitive-behavioural approaches or medication; in particular …

Agomelatine: a potential multitarget compound for neurodevelopmental disorders

R Savino, AN Polito, G Marsala, A Ventriglio… - Brain Sciences, 2023 - mdpi.com
Agomelatine (AGM) is one of the latest atypical antidepressants, prescribed exclusively for
the treatment of depression in adults. AGM belongs to the pharmaceutical class of melatonin …

Tolerance-inducing effect and properties of innate immune stimulation on chronic stress-induced behavioral abnormalities in mice

Y Gu, T Ye, P Tan, L Tong, J Ji, Y Gu, Z Shen… - Brain, Behavior, and …, 2021 - Elsevier
Over-activation of the innate immune system constitutes a risk factor for the development of
nervous system disorders but may reduce the severity of these disorders by inducing …

Adolescent microglia stimulation produces long-lasting protection against chronic stress-induced behavioral abnormalities in adult male mice

Y Wang, Z Hu, H Liu, Y Gu, M Ye, Q Lu, X Lu… - Brain, Behavior, and …, 2022 - Elsevier
Our previous studies had reported that microglia activation one day before stress exposure
prevented the behavioral abnormalities induced by chronic stress in adult mice, and a 10 …

Indole-3-carbinol selectively prevents chronic stress-induced depression-but not anxiety-like behaviors via suppressing pro-inflammatory cytokine production and …

S Pan, Y Ma, R Yang, X Lu, Q You, T Ye… - Frontiers in …, 2022 - frontiersin.org
Indole-3-carbinol (I3C), a phytochemical enriched in most cruciferous vegetables, has been
shown to display various biological activities such as anti-oxidative stress, anti-inflammation …

Ultrasensitive metasurface-based sensors for fingerprint spectra extraction of L-glutamate at ultra-low concentration

Y Wang, J Zhang, M Wang, G Song, B Zhang… - Optics …, 2024 - Elsevier
Abstract Terahertz-infrared (THz-infrared) absorption spectroscopy comprises distinctive
spectroscopic data that serves as a potent method for the detection and analysis of …

Relação entre dermatite atópica e transtorno de ansiedade na infância e adolescência: um protocolo de revisão de escopo

LOS Toledo - 2024 - arca.fiocruz.br
A dermatite atópica e os transtornos ansiosos afetam grande parte da população pediátrica.
A prevalência nesta faixa etária desta dermatite está em torno de 20%, e os transtornos …

ASPECTOS CLÍNICOS E TERAPÊUTICOS DO TRANSTORNO DE ANSIEDADE GENERALIZADA: UMA REVISÃO SISTEMÁTICA

IB Pestrini, AF Gonçalves… - LUMEN ET …, 2024 - periodicos.newsciencepubl.com
Objetivo: O objetivo geral deste estudo é analisar a produção científica sobre o Transtorno
de Ansiedade Generalizada (TAG), buscando identificar os principais aspectos clínicos …

Antidepressiva

R Taurines, M Gerlach - … im Kindes-und Jugendalter: Grundlagen und …, 2023 - Springer
Zusammenfassung „Antidepressiva “umfassen eine heterogene Klasse von Wirkstoffen, die
ursprünglich vorwiegend bei Patienten mit depressiven Symptomen eingesetzt wurden …