The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation

KD Moudgil, SH Venkatesha - International journal of molecular sciences, 2022 - mdpi.com
Inflammation is an integral part of autoimmune diseases, which are caused by dysregulation
of the immune system. This dysregulation involves an imbalance between pro-inflammatory …

A comprehensive review of the health perspectives of resveratrol

A Rauf, M Imran, HAR Suleria, B Ahmad, DG Peters… - Food & function, 2017 - pubs.rsc.org
Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

Recent advances on the anti-inflammatory and antioxidant properties of red grape polyphenols: in vitro and in vivo studies

T Magrone, M Magrone, MA Russo, E Jirillo - Antioxidants, 2019 - mdpi.com
In this review, special emphasis will be placed on red grape polyphenols for their antioxidant
and anti-inflammatory activities. Therefore, their capacity to inhibit major pathways …

Role of CCL2/CCR2 axis in the immunopathogenesis of rheumatoid arthritis: Latest evidence and therapeutic approaches

F Moadab, H Khorramdelazad, M Abbasifard - Life Sciences, 2021 - Elsevier
Evidence suggests that uncontrolled immune system responses and their components play
a significant role in developing rheumatoid arthritis (RA), which is considered an …

Mitochondrial dysfunction and oxidative stress in rheumatoid arthritis

MJ López-Armada, JA Fernández-Rodríguez… - Antioxidants, 2022 - mdpi.com
Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …

Resveratrol ameliorates rheumatoid arthritis via activation of SIRT1‐Nrf2 signaling pathway

G Wang, X Xie, lingli Yuan, J Qiu, W Duan, B Xu… - Biofactors, 2020 - Wiley Online Library
The present study was designed to explore the biological role of resveratrol (RES) in
rheumatoid arthritis (RA) and the underlying mechanism. The adjuvant‐induced arthritic rats …

Resveratrol role in autoimmune disease—a mini-review

ALB Oliveira, VVS Monteiro, KC Navegantes-Lima… - Nutrients, 2017 - mdpi.com
Autoimmune diseases are still considered to be pressing concerns due the fact that they are
leaders in death and disability causes worldwide. Resveratrol is a polyphenol derived from a …

Regulation of Sirt1 on energy metabolism and immune response in rheumatoid arthritis

Y Wu, W Fang, S Pan, S Zhang, D Li, Z Wang… - International …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a systemic autoimmune disease. Synovial hyperplasia and
persistent inflammation serve as its typical pathological manifestations, which ultimately lead …

Insights on the effects of resveratrol and some of its derivatives in cancer and autoimmunity: a molecule with a dual activity

E Gianchecchi, A Fierabracci - Antioxidants, 2020 - mdpi.com
In recent years, the interest in natural compounds exerting immunoregulatory effects has
enormously increased. Among these, the polyphenol resveratrol, found in a variety of foods …

Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro

Y Shen, X Fan, Y Qu, M Tang, Y Huang, Y Peng, Q Fu - Phytomedicine, 2022 - Elsevier
Background As a prolonged autoimmune disorder, rheumatoid arthritis (RA) is characterised
by synovial hyperplasia and the erosion of bone and cartilage. Magnoflorine (MAG) is the …