Breast cancer: Biology, biomarkers, and treatments

K Barzaman, J Karami, Z Zarei, A Hosseinzadeh… - International …, 2020 - Elsevier
During the past recent years, various therapies emerged in the era of breast cancer. Breast
cancer is a heterogeneous disease in which genetic and environmental factors are involved …

Recent advances in nanomaterial-based synergistic combination cancer immunotherapy

W Sang, Z Zhang, Y Dai, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
In recent years, conventional treatments including surgery, chemotherapy and radiotherapy
have been the main approaches in tumour therapy. Cancer immunotherapy is a new …

Recent advances in oligonucleotide therapeutics in oncology

H Xiong, RN Veedu, SD Diermeier - International Journal of Molecular …, 2021 - mdpi.com
Cancer is one of the leading causes of death worldwide. Conventional therapies, including
surgery, radiation, and chemotherapy have achieved increased survival rates for many types …

Mechanisms and therapeutic potentials of cancer immunotherapy in combination with radiotherapy and/or chemotherapy

WD Yu, G Sun, J Li, J Xu, X Wang - Cancer letters, 2019 - Elsevier
Immunotherapies based on T cells have gained significant success in the treatment of
diverse cancers, however, several limitations also exist, including low response, acquired …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Harnessing the immune system against cancer: current immunotherapy approaches and therapeutic targets

AR Kumar, AR Devan, B Nair, BS Vinod… - Molecular biology …, 2021 - Springer
Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar"
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …

CAR T cell therapy: a versatile living drug

RC De Marco, HJ Monzo, PM Ojala - International Journal of Molecular …, 2023 - mdpi.com
After seeing a dramatic increase in the development and use of immunotherapy and
precision medicine over the past few decades, oncological care now embraces the start of …

Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics

R Cuciniello, S Filosa, S Crispi - Journal of Experimental & Clinical Cancer …, 2021 - Springer
Short or small interfering RNAs (siRNAs) and microRNA (miRNAs) are molecules similar in
size and function able to inhibit gene expression based on their complementarity with mRNA …

Outsmarting trogocytosis to boost CAR NK/T cell therapy

F Ramezani, AR Panahi Meymandi, B Akbari… - Molecular Cancer, 2023 - Springer
Chimeric antigen receptor (CAR) NK and T cell therapy are promising immunotherapeutic
approaches for the treatment of cancer. However, the efficacy of CAR NK/T cell therapy is …

Targeting innate sensing in the tumor microenvironment to improve immunotherapy

Z Liu, C Han, YX Fu - Cellular & molecular immunology, 2020 - nature.com
The innate immune sensing pathways play critical roles in the defense against pathogen
infection, but their roles in cancer immunosurveillance and cancer therapies are less …