Inflammation in Glaucoma: From the back to the front of the eye, and beyond
C Baudouin, M Kolko, S Melik-Parsadaniantz… - Progress in retinal and …, 2021 - Elsevier
The pathophysiology of glaucoma is complex, multifactorial and not completely understood.
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …
Elevated intraocular pressure (IOP) and/or impaired retinal blood flow may cause initial optic …
[HTML][HTML] Glia–neuron interactions in the mammalian retina
The mammalian retina provides an excellent opportunity to study glia–neuron interactions
and the interactions of glia with blood vessels. Three main types of glial cells are found in …
and the interactions of glia with blood vessels. Three main types of glial cells are found in …
Effects of neurotrophic factors in glial cells in the central nervous system: expression and properties in neurodegeneration and injury
S Pöyhönen, S Er, A Domanskyi… - Frontiers in physiology, 2019 - frontiersin.org
Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …
nervous system and have been shown to play crucial roles in regulating both normal and …
Adaptive responses to neurodegenerative stress in glaucoma
DJ Calkins - Progress in retinal and eye research, 2021 - Elsevier
Glaucoma causes loss of vision through degeneration of the retinal ganglion cell (RGC)
projection to the brain. The disease is characterized by sensitivity to intraocular pressure …
projection to the brain. The disease is characterized by sensitivity to intraocular pressure …
Cholinergic nervous system and glaucoma: From basic science to clinical applications
The cholinergic system has a crucial role to play in visual function. Although cholinergic
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …
drugs have been a focus of attention as glaucoma medications for reducing eye pressure …
Targets of neuroprotection in glaucoma
S He, DL Stankowska, DZ Ellis… - Journal of Ocular …, 2018 - liebertpub.com
Progressive neurodegeneration of the optic nerve and the loss of retinal ganglion cells is a
hallmark of glaucoma, the leading cause of irreversible blindness worldwide, with primary …
hallmark of glaucoma, the leading cause of irreversible blindness worldwide, with primary …
Therapeutic drugs and devices for tackling ocular hypertension and glaucoma, and need for neuroprotection and cytoprotective therapies
NA Sharif - Frontiers in pharmacology, 2021 - frontiersin.org
Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …
The coma in glaucoma: Retinal ganglion cell dysfunction and recovery
Retinal ganglion cell (RGC) degeneration causes vision loss in patients with glaucoma, and
this has been generally considered to be irreversible due to RGC death. We question this …
this has been generally considered to be irreversible due to RGC death. We question this …
Early astrocyte redistribution in the optic nerve precedes axonopathy in the DBA/2J mouse model of glaucoma
Glaucoma challenges the survival of retinal ganglion cell axons in the optic nerve through
processes dependent on both aging and ocular pressure. Relevant stressors likely include …
processes dependent on both aging and ocular pressure. Relevant stressors likely include …
The morphological difference between glaucoma and other optic neuropathies
C Burgoyne - Journal of Neuro-ophthalmology, 2015 - journals.lww.com
The clinical phenomenon of cupping has 2 principal pathophysiologic components in all
optic neuropathies: prelaminar thinning and laminar deformation. We define prelaminar …
optic neuropathies: prelaminar thinning and laminar deformation. We define prelaminar …