Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

The peptidoglycan (PG) layer is a vital component of the bacterial cell wall that protects the
cell from rupturing due to internal pressure. Its ubiquity across the bacterial kingdom but not …

Natural products that contain distinctive chemical functionality can serve as useful starting
points to develop Nature's compounds into viable therapeutics. Peptide natural products, an …

The growing antimicrobial resistance crisis necessitates the discovery and development of
novel classes of antibiotics if a 'postantibiotic era'is to be avoided. Ribosomally synthesised …

Antibiotic resistance remains a global threat to human and animal health. Staphylococcus
aureus is an opportunistic pathogen that causes minor to life-threatening infections. The …

Chronic wounds with a long healing period are considered a worldwide problem. As an
important player in the wound healing process, keratinocyte growth factor (KGF) is one of the …

Ethnic fermented foods are known for their unique aroma, flavour, taste, texture and other
sensory properties preferred by every ethnic community in this world culturally as parts of …

The oral cavity hosts over 700 different microbial species that produce a rich reservoir of
bioactive metabolites critical to oral health maintenance. Over the last two decades, new …

The antimicrobial peptide (AMP) pleurocidin has a broad antimicrobial activity against Gram-
negative and Gram-positive bacteria by perturbation and permeabilizing their membranes; …