Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

Gliomas are primary brain tumours that are thought to derive from neuroglial stem or
progenitor cells. On the basis of their histological appearance, they have been traditionally …

Craniopharyngiomas are epithelial tumors that typically arise in the suprasellar region of the
brain. Patients experience substantial clinical sequelae from both extension of the tumors …

Glioblastoma is both the most common and lethal primary malignant brain tumor. Extensive
multiplatform genomic characterization has provided a higher-resolution picture of the …

Background Children with pediatric low‐grade gliomas (PLGG) are known to have excellent
10‐year survival rates; however the outcomes of adult survivors of PLGG are unknown. We …

RNA-seq by poly (A) selection is currently the most common protocol for whole
transcriptome sequencing as it provides a broad, detailed, and accurate view of the RNA …

Enabled by high-throughput sequencing approaches, epithelial cancers across a range of
tissue types are seen to harbor gene fusions as integral to their landscape of somatic …

The identification of distinct genetic and epigenetic profiles in different types of gliomas has
revealed novel diagnostic, prognostic, and predictive molecular biomarkers for refinement of …

Pilocytic astrocytomas are the primary tumors most frequently found in children and
adolescents, accounting for approximately 15.6% of all brain tumors and 5.4% of all gliomas …

Classification of gliomas involves the combination of histological features with molecular
biomarkers to establish an integrated histomolecular diagnosis. Here, we report on the …