Genomic prediction of (mal) adaptation across current and future climatic landscapes

T Capblancq, MC Fitzpatrick, RA Bay… - Annual Review of …, 2020 - annualreviews.org
Signals of local adaptation have been found in many plants and animals, highlighting the
heterogeneity in the distribution of adaptive genetic variation throughout species ranges. In …

Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions

S Hoban, JL Kelley, KE Lotterhos… - The American …, 2016 - journals.uchicago.edu
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …

dartr: An r package to facilitate analysis of SNP data generated from reduced representation genome sequencing

B Gruber, PJ Unmack, OF Berry… - Molecular ecology …, 2018 - Wiley Online Library
Although vast technological advances have been made and genetic software packages are
growing in number, it is not a trivial task to analyse SNP data. We announce a new r …

Opportunities and challenges of macrogenetic studies

DM Leigh, CB van Rees, KL Millette, MF Breed… - Nature Reviews …, 2021 - nature.com
The rapidly emerging field of macrogenetics focuses on analysing publicly accessible
genetic datasets from thousands of species to explore large-scale patterns and predictors of …

Comparing methods for detecting multilocus adaptation with multivariate genotype–environment associations

BR Forester, JR Lasky, HH Wagner… - Molecular …, 2018 - Wiley Online Library
Identifying adaptive loci can provide insight into the mechanisms underlying local
adaptation. Genotype–environment association (GEA) methods, which identify these loci …

pcadapt: an R package to perform genome scans for selection based on principal component analysis

K Luu, E Bazin, MGB Blum - Molecular ecology resources, 2017 - Wiley Online Library
The r package pcadapt performs genome scans to detect genes under selection based on
population genomic data. It assumes that candidate markers are outliers with respect to how …

A practical guide to environmental association analysis in landscape genomics

C Rellstab, F Gugerli, AJ Eckert, AM Hancock… - Molecular …, 2015 - Wiley Online Library
Landscape genomics is an emerging research field that aims to identify the environmental
factors that shape adaptive genetic variation and the gene variants that drive local …

Museum genomics

DC Card, B Shapiro, G Giribet, C Moritz… - Annual Review of …, 2021 - annualreviews.org
Natural history collections are invaluable repositories of biological information that provide
an unrivaled record of Earth's biodiversity. Museum genomics—genomics research using …

Reliable Detection of Loci Responsible for Local Adaptation: Inference of a Null Model through Trimming the Distribution of FST

MC Whitlock, KE Lotterhos - The American Naturalist, 2015 - journals.uchicago.edu
Loci responsible for local adaptation are likely to have more genetic differentiation among
populations than neutral loci. However, neutral loci can vary widely in their amount of …

Genomic insights into local adaptation and future climate-induced vulnerability of a keystone forest tree in East Asia

Y Sang, Z Long, X Dan, J Feng, T Shi, C Jia… - Nature …, 2022 - nature.com
Rapid global climate change is posing a substantial threat to biodiversity. The assessment of
population vulnerability and adaptive capacity under climate change is crucial for informing …