Diseases of the central nervous system (CNS) pose a significant health challenge, but
despite their diversity, they share many common features and mechanisms. For example …

Neuropathology in the human autoimmune disease multiple sclerosis (MS) is considered to
be mediated by autoreactive leukocytes, such as T cells, B cells, and macrophages …

Objective To examine the association between physical comorbidities and disability
progression in multiple sclerosis (MS). Methods We conducted a retrospective cohort study …

Endothelial cells closely interact with circulating lymphocytes. Aggression or activation of the
endothelium leads to an increased shedding of endothelial cell microparticles (MP) …

Vascular comorbidities are common in the general population and are associated with
adverse health outcomes. In people with multiple sclerosis (MS), an increasing amount of …

The MSRV (multiple sclerosis-associated retrovirus) belongs to the human endogenous
retrovirus HERV-W family. The envelope protein originating from the MSRV has been found …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central
nervous system wherein, after an initial phase of transient neurological defects, slow …

The pathophysiology of cerebral cortical lesions in multiple sclerosis (MS) is not understood.
We investigated cerebral cortex mi-crovessels during immune-mediated demyelination in …

The purpose of this work was to investigate the associations of serum cholesterol and
apolipoproteins with measures of blood-brain barrier (BBB) permeability and CNS …

The lower incidence of cardiovascular diseases in pre-menopausal women compared to
men is well-known documented. This protection has been largely attributed to the protective …