Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

Nanoscale MOFs: From synthesis to drug delivery and theranostics applications

M Ding, W Liu, R Gref - Advanced Drug Delivery Reviews, 2022 - Elsevier
Since the first report in 1989, Metal-Organic Frameworks (MOFs) self-assembled from metal
ions or clusters, as well as organic linkers, have attracted extensive attention. Due to their …

[HTML][HTML] Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

J Yang, D Dai, X Zhang, L Teng, L Ma, YW Yang - Theranostics, 2023 - ncbi.nlm.nih.gov
Cancer remains a severe threat to human health. To date, although various therapeutic
methods, including radiotherapy (RT), chemotherapy, chemodynamic therapy (CDT) …

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

L Liu, X Bai, MV Martikainen, A Kårlund… - Nature …, 2021 - nature.com
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive
nanomedical tools because of their unique properties such as immune escape, long blood …

The recent progress on metal–organic frameworks for phototherapy

Q Zheng, X Liu, Y Zheng, KWK Yeung, Z Cui… - Chemical Society …, 2021 - pubs.rsc.org
Some infectious or malignant diseases such as cancers are seriously threatening the health
of human beings all over the world. The commonly used antibiotic therapy cannot effectively …

MOF-on-MOF hybrids: Synthesis and applications

C Liu, J Wang, J Wan, C Yu - Coordination Chemistry Reviews, 2021 - Elsevier
Metal-organic frameworks (MOFs) are a promising class of porous crystalline materials with
diverse applications, the properties of which are dependent on their structures including …

[HTML][HTML] Metal-organic frameworks for advanced drug delivery

S He, L Wu, X Li, H Sun, T Xiong, J Liu, C Huang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Abstract Metal-organic frameworks (MOFs), comprised of organic ligands and metal
ions/metal clusters via coordinative bonds are highly porous, crystalline materials. Their …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …