[HTML][HTML] The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC)

R Farghadani, R Naidu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Breast cancer is a leadingcause of cancer-related deaths in women globally, with triple-
negative breast cancer (TNBC) being an aggressive subtype that lacks targeted therapies …

Dietary compounds as epigenetic modulating agents in cancer

Á Carlos-Reyes, JS López-González… - Frontiers in …, 2019 - frontiersin.org
Epigenetic mechanisms control gene expression during normal development and their
aberrant regulation may lead to human diseases including cancer. Natural phytochemicals …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Polyphenols as caloric-restriction mimetics and autophagy inducers in aging research

A Yessenkyzy, T Saliev, M Zhanaliyeva, AR Masoud… - Nutrients, 2020 - mdpi.com
It has been thought that caloric restriction favors longevity and healthy aging where
autophagy plays a vital role. However, autophagy decreases during aging and that can lead …

Effects and mechanisms of dietary bioactive compounds on breast cancer prevention

K Ganesan, B Du, J Chen - Pharmacological Research, 2022 - Elsevier
Breast cancer (BC) is the most often diagnosed cancer among females globally and has
become an increasing global health issue over the last decades. Despite the substantial …

Dietary antioxidants remodel DNA methylation patterns in chronic disease

M Beetch, S Harandi‐Zadeh, K Shen… - British journal of …, 2020 - Wiley Online Library
Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …

Polyamine metabolism and gene methylation in conjunction with one-carbon metabolism

K Soda - International journal of molecular sciences, 2018 - mdpi.com
Recent investigations have revealed that changes in DNA methylation status play an
important role in aging-associated pathologies and lifespan. The methylation of DNA is …

Another look at dietary polyphenols: Challenges in cancer prevention and treatment

R Arrigoni, A Ballini, L Santacroce… - Current Medicinal …, 2022 - ingentaconnect.com
Cancer is a pathology that impacts in a profound manner all over the world. The election
strategy against cancer often uses chemotherapy and radiotherapy, which, more often than …

Inhibition of Cancer Development by Natural Plant Polyphenols: Molecular Mechanisms

A Lyubitelev, V Studitsky - International Journal of Molecular Sciences, 2023 - mdpi.com
Malignant tumors remain one of the main sources of morbidity and mortality around the
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …

[HTML][HTML] The functional genomic studies of resveratrol in respect to its anti-cancer effects

L Huminiecki, J Horbańczuk - Biotechnology Advances, 2018 - Elsevier
Resveratrol has anti-cancer effects in vitro, and hypothetical chemopreventive effects in vivo.
Effects are pleiotropic, mediated by changes in expression of many genes and epigenetic …