Intermediate and high-risk non-muscle-invasive bladder cancer: an overview of epidemiology, burden, and unmet needs

K Grabe-Heyne, C Henne, P Mariappan… - Frontiers in …, 2023 - frontiersin.org
Bladder cancer ranks among the most common cancers globally. At diagnosis, 75% of
patients have non-muscle-invasive bladder cancer (NMIBC). Patients with low-risk NMIBC …

[HTML][HTML] An overview of immune checkpoint inhibitor toxicities in bladder cancer

A Mavadia, S Choi, A Ismail, A Ghose, JK Tan… - Toxicology Reports, 2024 - Elsevier
Bladder cancer is the tenth most prevalent malignancy worldwide, with a significant mortality
burden. Urothelial carcinoma (UC) is the most common histological subtype, and treatment …

Bladder cancer organoids as a functional system to model different disease stages and therapy response

M Minoli, T Cantore, D Hanhart, M Kiener… - Nature …, 2023 - nature.com
Abstract Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment
failure, suggesting that patients could benefit from a more personalized treatment approach …

Artificial intelligence to improve cytology performance in urothelial carcinoma diagnosis: results from validation phase of the French, multicenter, prospective …

T Lebret, X Paoletti, G Pignot, M Roumiguié… - World journal of …, 2023 - Springer
Purpose Cytology and cystoscopy, the current gold standard for diagnosing urothelial
carcinomas, have limits: cytology has high interobserver variability with moderate or not …

[HTML][HTML] Bladder cancer

S Leslie, T Soon-Sutton, N Aeddula - StatPearls, 2024 - statpearls.com
Bladder cancer, a prevalent malignancy affecting the urinary system, arises from the tissues
of the bladder, a hollow organ responsible for storing urine (see Image. Bladder Cancer …

Co-delivery of oxaliplatin prodrug liposomes with Bacillus Calmette-Guerin for chemo-immunotherapy of orthotopic bladder cancer

C Ma, X Zhong, R Liu, X Yang, Z Xie, Y Zhang… - Journal of Controlled …, 2024 - Elsevier
To reduce recurrence rate after transurethral resection of bladder tumor, long-term
intravesical instillations of Bacillus Calmette-Guérin (BCG) and/or chemotherapeutic drugs is …

Nanomedicine for combination urologic cancer immunotherapy

Y Tian, Z Liu, J Wang, L Li, F Wang, Z Zhu, X Wang - Pharmaceutics, 2023 - mdpi.com
Urologic cancers, particularly kidney, bladder, and prostate cancer, have a growing
incidence and account for about a million annual deaths worldwide. Treatments, including …

Bladder cancer cells interaction with lectin-coated surfaces under static and flow conditions

R Szydlak, IH Øvreeide, M Luty, T Zieliński… - International Journal of …, 2023 - mdpi.com
Aberrant expression of glycans, ie, oligosaccharide moiety covalently attached to proteins or
lipids, is characteristic of various cancers, including urothelial ones. The binding of lectins to …

Recent advancements in the diagnosis and treatment of non‐muscle invasive bladder cancer: evidence update of surgical concept, risk stratification, and BCG‐treated …

M Miyake, N Nishimura, T Fujii… - International Journal of …, 2023 - Wiley Online Library
In the management of non‐muscle invasive bladder cancer (NMIBC), disease progression
and long‐term control are determined by the intensity of delivered treatment and …

Urinary tract tumor organoids reveal eminent differences in drug sensitivities when compared to 2-dimensional culture systems

Y Wei, B Amend, T Todenhoefer, N Lipke… - International Journal of …, 2022 - mdpi.com
Generation of organoids from urinary tract tumor samples was pioneered a few years ago.
We generated organoids from two upper tract urothelial carcinomas and from one bladder …