Proximal tubulopathy: prime mover and key therapeutic target in diabetic kidney disease

RE Gilbert - Diabetes, 2017 - Am Diabetes Assoc
The current view of diabetic kidney disease, based on meticulously acquired ultrastructural
morphometry and the utility of measuring plasma creatinine and urinary albumin, has been …

Potential role of serum and urinary biomarkers in diagnosis and prognosis of diabetic nephropathy

CG Campion, O Sanchez-Ferras… - Canadian journal of …, 2017 - journals.sagepub.com
Purpose of review: Diabetic nephropathy (DN) is a progressive kidney disease caused by
alterations in kidney architecture and function, and constitutes one of the leading causes of …

[HTML][HTML] Renal function in diabetic nephropathy

PK Dabla - World journal of diabetes, 2010 - ncbi.nlm.nih.gov
Diabetic nephropathy is the kidney disease that occurs as a result of diabetes.
Cardiovascular and renal complications share common risk factors such as blood pressure …

Clinical outcome of renal tubular damage in chronic heart failure

K Damman, S Masson, HL Hillege… - European heart …, 2011 - academic.oup.com
Aims Both reduced glomerular filtration and increased urinary albumin excretion
independently determine outcome in patients with chronic heart failure (HF). However …

[HTML][HTML] Biomarkers in diabetic nephropathy: present and future

G Currie, G McKay, C Delles - World journal of Diabetes, 2014 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is the leading cause of end stage renal disease in the Western
world. Microalbuminuria (MA) is the earliest and most commonly used clinical index of DN …

Urinary markers of tubular injury in early diabetic nephropathy

T Fiseha, Z Tamir - International journal of nephrology, 2016 - Wiley Online Library
Diabetic nephropathy (DN) is a common and serious complication of diabetes associated
with adverse outcomes of renal failure, cardiovascular disease, and premature mortality …

[HTML][HTML] Urinary podocalyxin is an early marker for podocyte injury in patients with diabetes: establishment of a highly sensitive ELISA to detect urinary podocalyxin

M Hara, K Yamagata, Y Tomino, A Saito, Y Hirayama… - Diabetologia, 2012 - Springer
Aims/objective Nephropathy, a major complication of diabetes, is the leading cause of end-
stage renal disease. Recent studies have demonstrated that podocyte injury is involved in …

Diabetic nephropathy: traditional to proteomic markers

RN Moresco, MB Sangoi, JAM De Carvalho, E Tatsch… - Clinica chimica acta, 2013 - Elsevier
Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes and
it is defined as a rise in the urinary albumin excretion (UAE) rate and abnormal renal …

Neutrophil Gelatinase‐Associated Lipocalin (NGAL) and Kidney Injury Molecule 1 (KIM1) in patients with diabetic nephropathy: a cross‐sectional study and the effects …

SE Nielsen, KJ Schjoedt, AS Astrup, L Tarnow… - Diabetic …, 2010 - Wiley Online Library
Diabet. Med. 27, 1144–1150 (2010) Abstract Aims Our aim was to evaluate the markers of
tubulointerstitial damage, neutrophil gelatinase‐associated lipocalin (NGAL) and kidney …

Urinary tubular biomarkers in short-term type 2 diabetes mellitus patients: a cross-sectional study

W Fu, S Xiong, Y Fang, S Wen, M Chen, R Deng… - Endocrine, 2012 - Springer
The purpose of this study was to investigate the prevalence of tubular damage in short-term
(less than five years) type 2 diabetes mellitus (T2DM) patients and to explore the correlation …