Activatable fluorescence probes for “turn-on” and ratiometric biosensing and bioimaging: from NIR-I to NIR-II

C Chen, R Tian, Y Zeng, C Chu, G Liu - Bioconjugate Chemistry, 2020 - ACS Publications
The greatest advantage of activatable fluorescence probes (AFPs) is the inherent
responsiveness to manipulate spectroscopic properties by chemical/physical interactions …

Bio‐Conjugated Advanced Materials for Targeted Disease Theranostics

XL Hu, N Kwon, KC Yan, AC Sedgwick… - Advanced Functional …, 2020 - Wiley Online Library
Human beings are “machines” that use endogenously produced biomolecules as
“components” in signaling and for the maintenance of the body. These biomolecules consist …

Polarity mapping of cells and embryos by improved fluorescent solvatochromic pyrene probe

J Valanciunaite, E Kempf, H Seki… - Analytical …, 2020 - ACS Publications
Solvatochromic dyes enable sensing and imaging of biomolecular organization in living
systems by monitoring local polarity (lipophilicity), but most such dyes suffer from limited …

Photo-pH dual stimuli-responsive multicolor fluorescent polymeric nanoparticles for multicolor security ink, optical data encryption and zebrafish imaging

Z Lin, H Pan, Y Tian, J Tang, C Zhang, P Zhang… - Dyes and …, 2022 - Elsevier
Stimuli-responsive fluorescent polymeric nanoparticles are widely used in bioimaging, anti-
counterfeiting and data encryption due to their advantages of simple preparation, good …

Design of large stokes shift fluorescent proteins based on excited state proton transfer of an engineered photobase

EM Santos, W Sheng… - Journal of the …, 2021 - ACS Publications
The incredible potential for fluorescent proteins to revolutionize biology has inspired the
development of a variety of design strategies to address an equally broad range of …

Photoswitchable block copolymers based on main chain α-bisimines

LD Thai, TR Guimaraes, S Spann, AS Goldmann… - Polymer …, 2022 - pubs.rsc.org
We introduce linear diblock copolymers (BCPs) consisting of readily accessable and
photoswitchable α-bisimine units in the polymer backbone. The BCPs are prepared via a …

Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting

Y Dai, Y Sato, B Zhu, T Kitaguchi, H Kimura… - Chemical …, 2022 - pubs.rsc.org
Although intracellular biomarkers can be imaged with fluorescent dye (s)-labeled antibodies,
the use of such probes for precise imaging of intracellular biomarkers in living cells remains …

Imaging living obligate anaerobic bacteria with bilin-binding fluorescent proteins

HE Chia, T Zuo, NM Koropatkin, ENG Marsh… - Current research in …, 2020 - Elsevier
Fluorescent tools such as green fluorescent protein (GFP) have been used extensively as
reporters in biochemistry and microbiology, but GFP and other conventional fluorescent …

Regulation of absorption and Emission in a Protein/Fluorophore complex

EM Santos, I Chandra, Z Assar, W Sheng… - ACS Chemical …, 2024 - ACS Publications
Human cellular retinol binding protein II (hCRBPII) was used as a protein engineering
platform to rationally regulate absorptive and emissive properties of a covalently bound …

Dynamic covalent chemistry in live cells for organelle targeting and enhanced photodynamic action

F Liu, DI Danylchuk, B Andreiuk, AS Klymchenko - Chemical Science, 2022 - pubs.rsc.org
Organelle-specific targeting enables increasing the therapeutic index of drugs and localizing
probes for better visualization of cellular processes. Current targeting strategies require …