Restorative strategies after stroke are focused on the remodeling of cerebral endothelial
cells and brain parenchymal cells. The latter, ie, neurons, neural precursor cells and glial …

Dependence receptors are known to promote survival and positive signaling such as
proliferation, migration, and differentiation when activated, but to actively trigger apoptosis …

Aim Apoptosis of endothelial cells (ECs) is a crucial factor in blood-spinal cord barrier
(BSCB) disruption post spinal cord injury (SCI). Insulin-like growth factor-1 (IGF-1) is a …

Hallmark pathological features of brain trauma are axonal degeneration and demyelination
because myelin-producing oligodendrocytes (OLs) are particularly vulnerable to injury …

During development of the central nervous system not all axons are myelinated, and axons
may have distinct myelination patterns. Furthermore, the number of myelin sheaths formed …

Erythropoietin-producing hepatocellular carcinoma A4 (EphA4) is a transmembrane
receptor protein which is a part of the most prominent family of receptor tyrosine kinases …

Multiple cellular components are involved in the complex pathological process following
central nervous system (CNS) injury, including neurons, glial cells and endothelial cells …

Damage to the cerebrovascular network is a major contributor to dysfunction in patients
suffering from traumatic brain injury (TBI). Vessels are composed of lumen-forming …

Traumatic spinal cord injury (SCI) is a devastating condition that impacts over 300,000
individuals in the US alone. Depending on the severity of the injury, SCI can lead to varying …

The principal aim of present study was to assess the therapeutic efficacy of bone
morphogenetic protein-7 (BMP-7) induced differentiation of bone marrow mesenchymal …