Introduction Several isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1)
are connected with tumorigenesis. Hypoxic tumors overexpress CA IX and XII as a …

Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …

In this work, new isatin-based sulphonamides (6a-i, 11a-c, 12a-c) were designed and
synthesised as potential dual VEGFR-2 and carbonic anhydrase inhibitors with anticancer …

s-Triazine possesses an auspicious status in the field of drug discovery and development
owing to its presence in many naturally occurring compounds as well as commercially …

Mosquitoes, one of the deadliest animals on the planet, cause millions of fatalities each year
by transmitting several human illnesses. Synthetic pesticides were previously used to …

Mosquitoes are one of the deadliest and most hazardous animals on Earth, where they
transmit several diseases that kill millions of people annually. There is an ongoing search …

Abstract New 5‐cyano‐6‐oxo‐pyridine‐based sulfonamides (6a–m and 8a–d) were
designed and synthesized to potentially inhibit both the epidermal growth factor receptor …

S-triazines are a group of herbicides that are extensively applied to control broadleaf weeds
and grasses in agricultural production. They are mainly taken up through plant roots and are …

Thiadiazole and hydrazone derivatives (5a–5i) were synthesized and their chemical
structures were verified and described by 1H NMR, 13C NMR, and HRMS spectra. Three …

In the dynamic area of drug development, researchers have been urged to uncover and test
novel compounds with better effectiveness and fewer side effects in order to find more …