Molecular and biological rationale of hyperthermia as radio-and chemosensitizer

AL Oei, HP Kok, SB Oei, MR Horsman… - Advanced drug delivery …, 2020 - Elsevier
Mild hyperthermia, local heating of the tumour up to temperatures< 43° C, has been
clinically applied for almost four decades and has been proven to substantially enhance the …

Brachytherapy in breast cancer: an effective alternative

J Skowronek, A Chicheł - Menopause Review/Przegląd Menopauzalny, 2014 - termedia.pl
Purpose Breast cancer is the most frequently detected cancer in women in developed
countries and its incidence ranges from 25 to 30% of all cancers in women. Average age of …

Feasibility and safety assessment of magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU)-mediated mild hyperthermia in pelvic targets evaluated …

L Zhu, A Partanen, MR Talcott, HM Gach… - International Journal …, 2019 - Taylor & Francis
Purpose: To evaluate the feasibility and assess safety parameters of magnetic resonance-
guided high-intensity focused ultrasound (MRgHIFU)-mediated hyperthermia (HT; heating to …

Thermal Boost Combined with Interstitial Brachytherapy in Early Breast Cancer Conserving Therapy—Initial Group Long-Term Clinical Results and Late Toxicity

A Chicheł, W Burchardt, AJ Chyrek… - Journal of Personalized …, 2022 - mdpi.com
(1) In breast-conserving therapy (BCT), adjuvant radiation, including tumor bed boost, is
mandatory. Safely delivered thermal boost (TB) based on radio-sensitizing interstitial …

[HTML][HTML] Nrf2 silencing to inhibit proteolytic defense induced by hyperthermia in HT22 cells

P Bozaykut, NK Ozer, B Karademir - Redox Biology, 2016 - Elsevier
Nrf2 pathway has been known to be protective against cancer progression however recent
studies have revealed that the antioxidant activity of Nrf2 contributes to chemotherapy …

Characterization of magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU)-induced large-volume hyperthermia in deep and superficial targets in a …

L Zhu, D Lam, CP Pacia, HM Gach… - International Journal …, 2020 - Taylor & Francis
Purpose To characterize temperature fields and tissue damage profiles of large-volume
hyperthermia (HT) induced by magnetic resonance-guided high-intensity focused …

Thermal Boost to Breast Tumor Bed—New Technique Description, Treatment Application and Example Clinical Results

A Chicheł, W Burchardt, AJ Chyrek, G Bielęda… - Life, 2022 - mdpi.com
(1) Current breast-conserving therapy for breast cancer consists of a combination of many
consecutive treatment modalities. The most crucial goal of postoperative treatment is to …

Thermally boosted interstitial high-dose-rate brachytherapy in high-risk early-stage breast cancer conserving therapy—large cohort long-term results

A Chicheł, WM Burchardt, A Kluska… - Reports of Practical …, 2023 - journals.viamedica.pl
Background: Earl ys tag eh ig hr isk breast cancer (BC) is standardly treated with breas tc
onserving therapy (BCT), combined with systemic therapy and radiotherapy (RT)±tumor bed …

[HTML][HTML] The future of radiation oncology: considerations of young medical doctor

B Urbański - Reports of Practical Oncology & Radiotherapy, 2012 - Elsevier
Radiation therapy plays an increasingly important role in the management of cancer.
Currently, more than 50% of all cancer patients can expect to receive radiotherapy during …

Evaluation of clinical benefits achievable by using different optimization algorithms during real-time prostate brachytherapy

M Adamczyk, G Zwierzchowski, J Malicki, J Skowronek - Physica Medica, 2013 - Elsevier
BACKGROUND AND PURPOSE: High dose rate (HDR) brachytherapy is a clinically used
procedure in prostate cancer treatment. The purpose of this study was to present the …