Cycloaddition Reactions of Enamines

IV Efimov, DI Zhilyaev, LN Kulikova… - European Journal of …, 2023 - Wiley Online Library
This review includes information for around two last decades on cycloaddition reactions of
enamines with various agents in order to build carbo‐and heterocycles. In addition, the …

The extraordinary gravity of three atom 4π-components and 1, 3-dienes to C20-nXn fullerenes; a new gate to the future of Nano technology

SA Siadati, S Rezazadeh - Scientiae Radices, 2022 - yadda.icm.edu.pl
A quick glance to the adsorption, sensing, and energy storage abilities of C20 fullerene and
its derivatives indicate that this small carbon cluster may have extraordinary properties …

Transforming organic chemistry research paradigms: Moving from manual efforts to the intersection of automation and artificial intelligence

C Liu, Y Chen, F Mo - National Science Open, 2024 - nso-journal.org
Organic chemistry is undergoing a major paradigm shift, moving from a labor-intensive
approach to a new era dominated by automation and artificial intelligence (AI). This …

[4+ 1] cyclization of α-diazo esters and mesoionic N-heterocyclic olefins

Q Liang, Y Zeng, PAM Ocampo, H Zhu… - Chemical …, 2023 - pubs.rsc.org
Prompted by the recent stepwise mechanistic proposal for the Huisgen [3+ 2] cycloaddition
reaction between enamine and α-diazo ester, where the nucleophilic addition of the …

An Overlooked Pathway in 1, 3‐Dipolar Cycloadditions of Diazoalkanes with Enamines

L Li, P Mayer, DS Stephenson, AR Ofial… - Angewandte Chemie …, 2022 - Wiley Online Library
Methyl diazoacetate reacts with 1‐(N‐pyrrolidino) cycloalkenes to give products of 1, 3‐
dipolar cycloadditions and azo couplings. The kinetics and mechanisms of these reactions …

One-Bond-Nucleophilicity and-Electrophilicity Parameters: An Efficient Ordering System for 1, 3-Dipolar Cycloadditions

L Li, RJ Mayer, AR Ofial, H Mayr - Journal of the American …, 2023 - ACS Publications
Diazoalkanes are ambiphilic 1, 3-dipoles that undergo fast Huisgen cycloadditions with both
electron-rich and electron-poor dipolarophiles but react slowly with alkenes of low polarity …

Polycyclic Pyrazolidines by Tandem Diazomalonate Dipolar Cycloadditions and CpRu‐Catalyzed Carbene Additions

C Montagnon, JR Bultel, C Besnard… - … A European Journal, 2024 - Wiley Online Library
Thanks to the ability of diazo derivatives to react either as 1, 3‐dipoles and as carbenes after
dinitrogen extrusion, combinations of oxa or aza benzonorbornadienes and diazomalonates …

Nucleophilicities of Cyclic α‐Diazo Carbonyl Compounds

L Li, JR Hsu, H Zhao, AR Ofial - European Journal of Organic …, 2023 - Wiley Online Library
The one‐bond nucleophilic reactivities of seven cyclic α‐diazo carbonyl compounds in
dichloromethane were determined by analyzing the kinetics of their reactions with …

Microwave-assisted synthesis of pyrrolidinyl-spirooxindoles via tandem 1, 3-dipolar cycloaddition and oxidative dehydrogenation

H Tan, Y Xiang, J Huang, S Ren, C Lin, Z Xu, D Tang… - Tetrahedron, 2025 - Elsevier
An oxidant-free, microwave-promoted tandem 1, 3-dipolar cycloaddition and
dehydrogenation oxidation is achieved under environmentally friendly conditions, delivering …

Cyclobutane Formation by the Reaction of Ethenesulfonyl Fluoride with Dimethyl Diazomalonate

L Li, P Mayer, AR Ofial, H Mayr - European Journal of Organic …, 2022 - Wiley Online Library
Attempts to synthesize fluorosulfonyl‐substituted pyrazolines by Huisgen reactions (1, 3‐
dipolar cycloadditions) of dimethyl diazomalonate with ethenesulfonyl fluoride led to the …