Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis

T Gebremariam, S Alkhazraji, SSM Soliman, Y Gu… - Science …, 2019 - science.org
Mucorales are fungal pathogens that cause mucormycosis, a lethal angioinvasive disease.
Previously, we demonstrated that Rhizopus, the most common cause of mucormycosis …

Magnesium impairs Candida albicans immune evasion by reduced hyphal damage, enhanced β-glucan exposure and altered vacuole homeostasis

S Hans, Z Fatima, A Ahmad, S Hameed - PLoS One, 2022 - journals.plos.org
With a limited arsenal of available antifungal drugs and drug-resistance emergence,
strategies that seek to reduce Candida immune evasion and virulence could be a promising …

Staphylococcus aureus Phenol-Soluble Modulins α1–α3 Act as Novel Toll-Like Receptor (TLR) 4 Antagonists to Inhibit HMGB1/TLR4/NF-κB Signaling Pathway

M Chu, M Zhou, C Jiang, X Chen, L Guo… - Frontiers in …, 2018 - frontiersin.org
Phenol-soluble modulins (PSMs) have recently emerged as key virulence determinants,
particularly in highly aggressive Staphylococcus aureus isolates. These peptides contribute …

Cellular and Molecular Response of Macrophages THP-1 during Co-Culture with Inactive Trichophyton rubrum Conidia

G Gonzalez Segura, BA Cantelli, K Peronni… - Journal of Fungi, 2020 - mdpi.com
Trichophyton rubrum is causing an increasing number of invasive infections, especially in
immunocompromised and diabetic patients. The fungal invasive infectious process is …

Response of Human Neutrophil Granulocytes to the Hyphae of the Emerging Fungal Pathogen Curvularia lunata

EJ Tóth, M Varga, M Takó, M Homa, O Jáger… - Pathogens, 2020 - mdpi.com
Curvularia lunata is an ascomycete filamentous fungus causing local and invasive
phaeohyphomycoses in both immunocompromised and immunocompetent patients …

Host cell-type and pathogen-specific immunomodulatory functions of macrophage migration inhibitory factor (MIF) in infectious keratitis

S Ghosh, AHH Khathun, GS Athulya, P Vignesh… - Experimental Eye …, 2023 - Elsevier
Therapeutic management of inflammation in infectious keratitis (IK) requires new strategy
and targets for selective immunomodulation. Targeting host cell-type specific inflammatory …

Expression of Cytokine Profiles in Human THP-1 Cells during Phase Transition of Talaromyces marneffei

F Shu, P Thammasit, K Pruksaphon, JD Nosanchuk… - Pathogens, 2022 - mdpi.com
Talaromyces marneffei, a dimorphic fungus, exhibits temperature-dependent growth,
existing in a filamentous form at 25° C and as a yeast at 37° C. Several studies have …

Parietal composition of Lichtheimia corymbifera: Differences between spore and germ tube stages and host-pathogen interactions

K Lecointe, P Coulon, F Krzewinski, R Charlet… - Medical …, 2023 - academic.oup.com
The molecular composition and structural organization of the cell wall of filamentous fungi
underlie the ability of the host to identify them as pathogens. Although the organization of the …

Differential inflammatory response to Aspergillus flavus and Candida albicans infection in human retinal pigment epithelial cells: role in treatment of endophthalmitis

J Gandhi, J Joseph - Journal of Medical Mycology, 2021 - Elsevier
Objective Fungal endophthalmitis is an emerging vision-threatening complication in tropical
countries and the Retinal pigment epithelial cells (RPE) are said to play a major role in the …

[HTML][HTML] Evaluation of blood cell viability rate, gene expression, and O-GlcNAcylation profiles as indicative signatures for fungal stimulation of salmonid cell models

AR Magray, JM Ribera, L Isernhagen, SP Galuska… - Molecular …, 2022 - Elsevier
Fungal diseases of fish are a significant economic problem in aquaculture. Using high-
throughput expression analysis, we identified potential transcript markers in primary head …