Since the outbreak of COVID-19 disease, a bidirectional interaction between kidney disease
and the progression of COVID-19 has been demonstrated. Kidney disease is an …

Glycation and glycosylation are non-enzymatic and enzymatic reactions, respectively, of
glucose, glucose metabolites, and other reducing sugars with different substrates, such as …

Rapid eye movement (REM) sleep is implicated learning and memory (L/M) functions and
hippocampal long-term potentiation (LTP). Here, we demonstrate that REM sleep …

Renal proximal tubule cells (PTECs) act as urine gatekeepers, constantly and efficiently
avoiding urinary protein waste through receptor-mediated endocytosis. Despite its …

O-GlcNAcylation is a post-translational modification (PTM) that regulates a wide range of
cellular functions and has been associated with multiple metabolic diseases in various …

The large (∼ 600 kDa) endocytosis receptor megalin/low-density lipoprotein receptor-
related protein 2 is highly expressed at the apical membrane of proximal tubular epithelial …

The ablation of renal nerves, by destroying both the sympathetic and afferent fibers, has
been shown to be effective in lowering blood pressure in resistant hypertensive patients …

Primary cilia are sensory organelles built and maintained by intraflagellar transport (IFT)
multiprotein complexes. Deletion of several IFT-B genes attenuates polycystic kidney …

Fetal kidney development is characterized by increased uptake of glucose, ATP production
by glycolysis, and upregulation of mammalian target of rapamycin (mTOR) and hypoxia …

Kidneys maintain internal milieu homeostasis through a well-regulated manipulation of body
fluid composition. This task is performed by the correlation between structure and function in …