Therapeutic drug monitoring by dried blood spot: progress to date and future directions

AJ Wilhelm, JCG den Burger, EL Swart - Clinical pharmacokinetics, 2014 - Springer
This article discusses dried blood spot (DBS) sampling in therapeutic drug monitoring
(TDM). The most important advantages of DBS sampling in TDM are the minimally invasive …

[HTML][HTML] Advantages and challenges of dried blood spot analysis by mass spectrometry across the total testing process

R Zakaria, KJ Allen, JJ Koplin, P Roche, RF Greaves - Ejifcc, 2016 - ncbi.nlm.nih.gov
Methods To address these aims we performed a key word search of the PubMed and
MEDLINE online databases in conjunction with individual manual searches to gather …

Emerging trends in paper spray mass spectrometry: Microsampling, storage, direct analysis, and applications

BS Frey, DE Damon… - Mass spectrometry …, 2020 - Wiley Online Library
Recent advancements in the sensitivity of chemical instrumentation have led to increased
interest in the use of microsamples for translational and biomedical research. Paper …

Optimization of gradient reversed phase high performance liquid chromatography analysis of acetaminophen oxidation metabolites using linear and non-linear …

J Vanova, D Malinak, R Andrys, M Kubat… - … of Chromatography A, 2022 - Elsevier
Acetaminophen (paracetamol, APAP) is one of the most widely used drugs worldwide.
Unfortunately, its overdose, which is caused by predominant oxidation of APAP, can lead to …

Procedures and practices for the validation of bioanalytical methods using dried blood spots: a review

NGL Jager, H Rosing, JHM Schellens, JH Beijnen - Bioanalysis, 2014 - Taylor & Francis
Dried blood spot (DBS) sampling, the collection of whole blood samples on paper, is an
emerging technique used for bioanalytical methods. Several analytical challenges, such as …

Protective effect of hyperoside against acetaminophen (APAP) induced liver injury through enhancement of APAP clearance

W Xie, Z Jiang, J Wang, X Zhang, MF Melzig - Chemico-biological …, 2016 - Elsevier
Acetaminphen (APAP) overdose leads to severe hepatotoxicity. Apocynum venetum L.(A.
venetum) possess potent hepatoprotective effect. Hyperoside is one of the major …

Comparison of the quantification of acetaminophen in plasma, cerebrospinal fluid and dried blood spots using high-performance liquid chromatography–tandem mass …

RR Taylor, KL Hoffman, B Schniedewind… - … of pharmaceutical and …, 2013 - Elsevier
Acetaminophen (paracetamol, N-(4-hydroxyphenyl) acetamide) is one of the most commonly
prescribed drugs for the management of pain in children. Quantification of acetaminophen in …

Dried blood spot sampling in protein and peptide bioanalysis: optimism, experience, and the path forward

S Kaareddy, P Dhakne, M Pillai, N Rajput… - International Journal of …, 2023 - Springer
Dried blood spot (DBS) based microsampling is an emerging approach that requires a
minimally invasive procedure. It is being increasingly used in metabolic screening …

Volumetric absorptive microsampling as an alternative sampling strategy for the determination of paracetamol in blood and cerebrospinal fluid

L Delahaye, E Dhont, P De Cock, P De Paepe… - Analytical and …, 2019 - Springer
In the field of bioanalysis, dried matrix spot sampling is increasingly receiving interest, as
this alternative sampling strategy offers many potential benefits over traditional sampling …

Therapeutic drug monitoring in dried blood spots using liquid microjunction surface sampling and high resolution mass spectrometry

T Gaissmaier, M Siebenhaar, V Todorova, V Hüllen… - Analyst, 2016 - pubs.rsc.org
Dried blood spots (DBS) are a versatile and stable tool for direct clinical blood analysis.
Ambient high-resolution mass spectrometry is emerging as a method of choice for their …