Recent progress in 1, 2, 4-triazolo [1, 5-a] pyrimidine chemistry

G Fischer - Advances in heterocyclic chemistry, 2007 - Elsevier
Publisher Summary 1, 2, 4-Triazolo [1, 5-a] pyrimidines (TPs) play an important role in
pharmaceutics, agrochemistry, photography, and other fields. They attract attention in …

Synthetic aspects of condensed pyrimidine derivatives

M Devi, S Jaiswal, J Dwivedi… - Current Organic …, 2021 - ingentaconnect.com
The present review focuses on the synthesis of two heteroatoms containing sixmembered
heterocyclic compounds, ie, pyrimidine. In this review, a number of pyrimidine derivatives …

Advances in the solid-phase synthesis of pyrimidine derivatives

EP Aparna, KS Devaky - ACS Combinatorial Science, 2019 - ACS Publications
This Review describes the existing synthetic approaches for the solid-phase synthesis (SPS)
of differently substituted and fused pyrimidine derivatives. These synthetic strategies are …

Fluorinated 1,2,4‐Triazolo[1,5‐a]pyrimidine‐6‐carboxylic Acid Derivatives as Antimycobacterial Agents

HM Abdel‐Rahman, NA El‐Koussi… - Archiv der Pharmazie …, 2009 - Wiley Online Library
Abstract A series of fluorinated 1, 2, 4‐triazolo [1, 5‐a] pyrimidine‐6‐carboxylic acid
derivatives was designed and synthesized as fluoroquinolone analogues. The synthesized …

EMCA and DEEM as Michael reagents used in organic synthesis

A Kaczor, D Matosiuk - Current Organic Chemistry, 2005 - ingentaconnect.com
This paper reviews on application of two Michael reagents-ethyl
ethoxymethylenecyanoacetate (EMCA) and diethyl ethoxymethylenemalonate (DEEM …

Structure-activity relationships of quinolones

LA Mitscher, Z Ma - Fluoroquinolone antibiotics, 2003 - Springer
The first of the antiinfective agents belonging to the quinolone class was discovered 50
years ago. Since that time many thousands of analogs have been prepared and nearly two …

Photocatalytic synthesis of 2-amino-4, 6-diarylpyrimidines using nanoTiO2

EP Aparna, D Mathew, A Thomas, N Rakesh… - … of Photochemistry and …, 2020 - Elsevier
Abstract Photocatalytic synthesis of 2-amino-4, 6-diarylpyrimidines was carried out by using
nano TiO 2. The method follows a green route by avoiding the use of toxic organic solvents …

Synthesis and Antibacterial Screening Of Some 2, 5, 7triaryl-1, 2, 4-Triazolo [1, 5-a] PYRIMIDINES

NA El-Koussi, FA Omar, SA Abdel-Aziz… - Bulletin of …, 2004 - bpsa.journals.ekb.eg
Three novel series of 5, 7-diaryl-2-(pyridyl)-1, 2, 4-triazolo [1, 5-a] pyrimidines were prepared
as antibacterial and antifungal agents. The triazolopyrimidines (21-23) am were synthesized …

[PDF][PDF] SYNTHESIS OF 2-TRIFLUOROMETHYL-4, 7-DIHYDRO-7-OXO-(1, 2, 4) TRIAZOLO [1, 5-a] PYRIMIDINE-6-CARBOXYLIC ACID DERIVATIVES AS POTENTIAL …

NA El-Koussi - Bulletin of Pharmaceutical Sciences Assiut …, 2008 - journals.ekb.eg
Syntheses of the target compounds were achieved by reaction of3-amino-5-trifluoromethyl-
1, 2, 4-triazole 1 and diethylethoxymethylenemalonate (DEEM) in glacial acetic acid to …

[引用][C] Preparation of 2, 7-diaminosubstituted-[1, 2, 4] triazolo [1, 5-a] pyrimidine-6-carbonitriles by solid-phase synthesis.

CL Cavallaro, LS Harikrishnan, F Chi… - Journal of …, 2007 - europepmc.org
Preparation of 2,7-diaminosubstituted-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitriles by solid-phase
synthesis. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …