Looking ahead: ethical and social challenges of somatic gene therapy for sickle cell disease in Africa
Somatic gene therapy will be one of the most exciting practices of genetic medicine in Africa
and is primed to offer a “new life” for persons living with sickle cell disease (SCD). Recently …
and is primed to offer a “new life” for persons living with sickle cell disease (SCD). Recently …
Liver and renal biochemical profiles of people with sickle cell disease in Africa: a systematic review and meta-analysis of case-control studies
Background Sickle cell disease (SCD) is a genetic blood disorder characterized by a painful
vaso-occlusive crisis due to the sickling of red blood cells in capillaries. Complications often …
vaso-occlusive crisis due to the sickling of red blood cells in capillaries. Complications often …
Sickle cell disease and assessment of energy metabolism and serum cortisol in Lubumbashi
TK Edouard, KI Eric, LA Philomene, BE Michel… - World Journal of …, 2024 - wjarr.co.in
Introduction: Sickle cell disease is an inherited red blood cells disorder which leads to
oxidative stress and resulting in the disturbance of energy metabolism. Objective: The aim of …
oxidative stress and resulting in the disturbance of energy metabolism. Objective: The aim of …
Glomerular filtration rate in children with sickle cell disease in the Eastern Region of Saudi Arabia
AM Zayed, A Zayed, S Almohaimeed, A Eltayeb… - 2024 - researchsquare.com
Methods A retrospective cross-sectional study was performed on 114 Saudi children with
SCD aged 1-14 years who attended the pediatric hematology clinic in a steady state. Renal …
SCD aged 1-14 years who attended the pediatric hematology clinic in a steady state. Renal …
[PDF][PDF] Avaliação do perfil de expressão gênica de células endoteliais progenitoras de pacientes com anemia falciforme e acidente vascular cerebral
JNP de Castro - 2023 - repositorio.unicamp.br
RESUMO A anemia falciforme (AF) é uma hemoglobinopatia resultante de uma única
mutação em homozigose no sétimo códon do gene da beta-globina. No entanto, há uma …
mutação em homozigose no sétimo códon do gene da beta-globina. No entanto, há uma …
Toward building a comprehensive human pan-genome: The SEN-GENOME project
A Gaye, ARG Sene, M Gadji, A Deme, A Cisse… - The American Journal of …, 2024 - cell.com
The human reference genome (GRCh38), primarily sourced from individuals of European
descent, falls short in capturing the vast genetic diversity across global populations. Efforts to …
descent, falls short in capturing the vast genetic diversity across global populations. Efforts to …