The critical role of the coronary microvascular compartment and its invasive functional
assessment has become apparent in light of the significant proportion of patients presenting …

Heart failure with preserved ejection fraction (HFpEF) currently accounts for approximately
half of all new heart failure cases in the community. HFpEF is closely associated with chronic …

Objectives This study investigated sex differences in coronary flow reserve (CFR) and the
index of microcirculatory resistance (IMR) in patients with angina in the absence of …

Background—The index of microcirculatory resistance (IMR) is a quantitative and specific
index for coronary microcirculation. However, the distribution and determinants of IMR have …

Background—Recent evidence suggests that the diagnostic accuracy of myocardial
perfusion imaging is improved by quantifying stress myocardial blood flow (MBF) in absolute …

Although concomitant coronary artery disease (CAD) is frequent in patients with severe
aortic stenosis (AS), hemodynamic assessment of CAD severity in patients undergoing valve …

Coronary artery disease (CAD) is a leading global cause of morbidity and mortality, and
improvements in the diagnosis and treatment of CAD can reduce the health and economic …

Background The index of microvascular resistance (IMR) is an established tool to assess the
status of coronary microcirculation. However, the need for a pressure wire and hyperemic …

Background: Approximately half of the patients presenting with ST-segment–elevation
myocardial infarction (STEMI) have multivessel disease. The physiology of the nonculprit …

Despite the current evidence supporting clinical benefits of fractional flow reserve (FFR), its
uptake in the cardiac catheterization laboratory has been slow due to procedural cost and …