Chemometrics tools used in analytical chemistry: An overview

N Kumar, A Bansal, GS Sarma, RK Rawal - Talanta, 2014 - Elsevier
This article presents various important tools of chemometrics utilized as data evaluation
tools generated by various hyphenated analytical techniques including their application …

QSRR: quantitative structure-(chromatographic) retention relationships

R Kaliszan - Chemical reviews, 2007 - ACS Publications
At the current state of development of chemistry, it appears easier to synthesize a compound
with a definite chemical structure than with a certain required property. Usually, reaction …

High throughput physicochemical profiling for drug discovery

EH Kerns - Journal of pharmaceutical sciences, 2001 - Elsevier
The drug development bottlenecks of attrition and development time are being addressed by
acquiring a profile of the candidate's physicochemical and physiological properties during …

[图书][B] Pharmacokinetics and metabolism in drug design

R Mannhold, H Kubinyi, G Folkers - 2012 - books.google.com
In this new edition of a bestseller, all the contents have been brought upto-date by
addressing current standards and best practices in the assessment and prediction of …

Comprehensive liquid chromatography: fundamental aspects and practical considerations—a review

I François, K Sandra, P Sandra - Analytica chimica acta, 2009 - Elsevier
In the quest for separation techniques capable of generating high peak capacities,
comprehensive two-dimensional (2D) liquid chromatography (LC× LC) is a performant …

Implementations of two-dimensional liquid chromatography

G Guiochon, N Marchetti, K Mriziq… - Journal of Chromatography …, 2008 - Elsevier
Today scientists must deal with complex samples that either cannot be adequately
separated using one-dimensional chromatography or that require an inordinate amount of …

Using a material property library to find surrogate materials for pharmaceutical process development

MS Escotet-Espinoza, S Moghtadernejad, J Scicolone… - Powder technology, 2018 - Elsevier
Material properties are known to have a significant impact on pharmaceutical manufacturing
performance, particularly for solid product processes. Evaluating the performance of a …

Review on modelling aspects in reversed-phase liquid chromatographic quantitative structure–retention relationships

R Put, Y Vander Heyden - Analytica chimica acta, 2007 - Elsevier
In the literature an increasing interest in quantitative structure–retention relationships
(QSRR) can be observed. After a short introduction on QSRR and other strategies proposed …

[HTML][HTML] Protein profile analysis of tear fluid with hyphenated HPLC-UV LED-induced fluorescence detection for the diagnosis of dry eye syndrome

SS Adigal, SV Bhandary, N Hegde, VR Nidheesh… - RSC …, 2023 - pubs.rsc.org
Tear fluid contains organic and inorganic constituents, variations in their relative
concentrations could provide valuable information and can be useful for the detection of …

Evaluation of sugar, free amino acid, and organic acid compositions of different varieties of vegetable soybean (Glycine max [L.] Merr)

J Song, C Liu, D Li, Z Gu - Industrial Crops and Products, 2013 - Elsevier
Vegetable soybean is rich in nutrients and is known to possess favourable sensory
characteristics, which contribute to its importance and popularity as a consumed crop …