The development and application of the free-electron X-ray laser (XFEL) to structure and
dynamics in biology since its inception in 2009 are reviewed. The research opportunities …

Crystallography has made a notable contribution to our knowledge of structural biology. For
traditional crystallography experiments, the growth of crystals with large size and high …

The Sample Environment and Characterization (SEC) group of the European X-ray Free-
Electron Laser (EuXFEL) develops sample delivery systems for the various scientific …

Ultra-bright femtosecond X-ray pulses generated by X-ray free-electron lasers (XFELs) can
be used to image high-resolution structures without the need for crystallization. For this …

The advent of ultrafast X-ray free-electron lasers (XFELs) opens the tantalizing possibility of
the atomic-resolution imaging of reproducible objects such as viruses, nanoparticles, single …

The complex cellular structures maintain the biological activities of cells. Revealing the
structure of cells at the nanoscale is of great significance for cell biology. Coherent X-ray …

Single molecule x-ray scattering experiments using free-electron lasers hold the potential to
resolve biomolecular structures and structural ensembles. However, molecular electron …

Serial femtosecond crystallography (SFX) with X-ray free electron lasers (XFELs) is an
emerging field for structural biology. One of its major impacts lies in the ability to reveal the …

Capturing protein structural dynamics in real-time has tremendous potential in elucidating
biological functions and providing information for structure-based drug design. While time …

Serial femtosecond crystallography (SFX) uses X-ray pulses from free-electron laser (FEL)
sources that can outrun radiation damage and thereby overcome long-standing limits in the …