Global epidemiology of rheumatoid arthritis

A Finckh, B Gilbert, B Hodkinson, SC Bae… - Nature Reviews …, 2022 - nature.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

[HTML][HTML] Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

A Lerner, T Matthias - Autoimmunity reviews, 2015 - Elsevier
The incidence of autoimmune diseases is increasing along with the expansion of industrial
food processing and food additive consumption. The intestinal epithelial barrier, with its …

A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease: comorbidity and mortality

C Hyldgaard, O Hilberg, AB Pedersen… - Annals of the …, 2017 - ard.bmj.com
Objectives To compare mortality risks in patients with rheumatoid arthritis-associated
interstitial lung disease (RA-ILD) and patients with RA without ILD. Design Matched cohort …

Improvement in 5-year mortality in incident rheumatoid arthritis compared with the general population—closing the mortality gap

D Lacaille, JA Avina-Zubieta, EC Sayre… - Annals of the …, 2017 - ard.bmj.com
Objective Excess mortality in rheumatoid arthritis (RA) is expected to have improved over
time, due to improved treatment. Our objective was to evaluate secular 5-year mortality …

Preclinical assessment of inflammatory pain

MM Muley, E Krustev… - CNS neuroscience & …, 2016 - Wiley Online Library
While acute inflammation is a natural physiological response to tissue injury or infection,
chronic inflammation is maladaptive and engenders a considerable amount of adverse pain …

Rheumatoid arthritis is getting less frequent—results of a nationwide population-based cohort study

A Abhishek, M Doherty, CF Kuo, CD Mallen… - …, 2017 - academic.oup.com
Objectives. The objectives of this study were to examine changes in the incidence and
prevalence of RA between 1990 and 2014 and to explore if there is any geographic …

The epithelial barrier theory and its associated diseases

N Sun, I Ogulur, Y Mitamura, D Yazici, Y Pat, X Bu… - Allergy, 2024 - Wiley Online Library
The prevalence of many chronic noncommunicable diseases has been steadily rising over
the past six decades. During this time, over 350,000 new chemical substances have been …

Early medication use in new-onset rheumatoid arthritis may delay joint replacement: results of a large population-based study

CS Moura, M Abrahamowicz, ME Beauchamp… - Arthritis research & …, 2015 - Springer
Introduction Use of disease-modifying anti-rheumatic drugs (DMARDs) in rheumatoid
arthritis (RA) may prevent joint damage and potentially reduce joint replacement surgeries …

Trends in excess mortality among patients with rheumatoid arthritis in Ontario, Canada

J Widdifield, S Bernatsky, JM Paterson… - Arthritis care & …, 2015 - Wiley Online Library
Objective To evaluate excess mortality over time, comparing rheumatoid arthritis (RA)
patients with the general population. Methods We computed all‐cause mortality rates among …

Development and validation of an administrative data algorithm to estimate the disease burden and epidemiology of multiple sclerosis in Ontario, Canada

J Widdifield, NM Ivers, J Young… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background: Few studies have assessed the accuracy of administrative data for identifying
multiple sclerosis (MS) patients. Objectives: To validate administrative data algorithms for …