Genomic instability is a primary cause and fundamental feature of human cancer. However,
all cancer cell genotypes generally translate into several common pathophysiological …

Surface charge on biomaterials is emerging as a crucial determinant of regulating cells
responses impacting cells signaling in tissue treatment. The dynamic cell-material …

The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a
wide array of signaling events, leading to protective (eg, cytoskeletal rearrangement) and …

Apoptosis is a conserved homeostatic process critical for organ and tissue morphogenesis,
development, and senescence. This form of programmed cell death also participates in the …

Biophysical signaling, an integral regulator of long-term cell behavior in both excitable and
non-excitable cell types, offers enormous potential for modulation of important cell functions …

Reduced glutathione (L-γ-glutamyl-L-cysteinyl-glycine, GSH) is the prevalent low-molecular-
weight thiol in mammalian cells. It is formed in a two-step enzymatic process including, first …

The envelope (E) protein from coronaviruses is a small polypeptide that contains at least
one α-helical transmembrane domain. Absence, or inactivation, of E protein results in …

Severe peripheral nerve injuries are threatening the life quality of human beings. Current
clinical treatments contain some limitations and therefore extensive research and efforts are …

Changes in the intracellular redox environment of cells have been reported to be critical for
the activation of apoptotic enzymes and the progression of programmed cell death …

The loss of cell volume or cell shrinkage has been a morphological hallmark of the
programmed cell death process known as apoptosis. This isotonic loss of cell volume has …