Perineuronal nets (PNNs) were shown to be markedly altered in subjects with
schizophrenia. In particular, decreases of PNNs have been detected in the amygdala …

Background The human natural killer-1 (HNK-1) carbohydrate, a unique trisaccharide
possessing sulfated glucuronic acid in a non-reducing terminus (HSO 3-3GlcAß1-3Galß1 …

Perineuronal nets (PNNs) are pericellular coats of condensed matrix that enwrap the cell
bodies and dendrites of many adult central nervous system (CNS) neurons. These …

Subsets of GABAergic neurons are surrounded by perineuronal nets (PNNs), which play a
critical role in the regulation of neural plasticity and neuroprotection. Although the plant …

Fibrosis is defined as the thickening and scarring of connective tissue, usually as a
consequence of tissue damage. The central nervous system (CNS) is special in the sense …

The SAM strain of mice is actually a group of related inbred strains consisting of a series of
SAMP (accelerated senescence-prone) and SAMR (accelerated senescence-resistant) …

Abstract The Senescence-Accelerated Mouse (SAM) represents a group of inbred mouse
strains developed as a model for the study of human aging and age-related diseases …

The mechanisms of aging in the brain and the subsequent decrease in cognitive abilities
remain elusive. While most studies refer to research conducted in old and senile animals …

Congenital muscular dystrophies (CMDs) with associated brain abnormalities are a group of
disorders characterized by muscular dystrophy and brain and eye abnormalities that are …

Introduction 3. CS proteoglycans and biosynthesis of CS 3.1. Structure of CS proteoglycans
3.2. Biosynthesis and structure of CS 4. Functional significance of structural variation of CS …