A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: A focus on signaling pathways interplay

AS Doghish, A Ismail, MA Elrebehy… - … -Research and Practice, 2022 - Elsevier
Lung cancer (LC) is the most common cancer-related death globally, and many efforts have
been made to improve the patient care of LC patients, as well as the development of efficient …

The roles of MicroRNA in lung cancer

KL Wu, YM Tsai, CT Lien, PL Kuo, JY Hung - International journal of …, 2019 - mdpi.com
Lung cancer is the most devastating malignancy in the world. Beyond genetic research,
epigenomic studies—especially investigations of microRNAs—have grown rapidly in …

Current landscape of therapeutic resistance in lung cancer and promising strategies to overcome resistance

A Ashrafi, Z Akter, P Modareszadeh, P Modareszadeh… - Cancers, 2022 - mdpi.com
Simple Summary Despite an initial response to therapy, many lung cancer patients
inevitably develop resistance to therapy leading to decreased duration of response and …

Omental cancer‐associated fibroblast‐derived exosomes with low microRNA‐29c‐3p promote ovarian cancer peritoneal metastasis

Q Han, S Tan, L Gong, G Li, Q Wu, L Chen… - Cancer …, 2023 - Wiley Online Library
Ovarian cancer (OC) is characterized by frequent widespread peritoneal metastasis. Cancer‐
associated fibroblasts (CAFs) represent a critical stromal component of metastatic niche and …

Progress in delivery of siRNA-based therapeutics employing nano-vehicles for treatment of prostate cancer

M Ashrafizadeh, K Hushmandi, E Rahmani Moghadam… - Bioengineering, 2020 - mdpi.com
Prostate cancer (PCa) accounts for a high number of deaths in males with no available
curative treatments. Patients with PCa are commonly diagnosed in advanced stages due to …

miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro

FM Troschel, N Böhly, K Borrmann, T Braun… - tumor …, 2018 - journals.sagepub.com
Effectively targeting cancer stem cells, a subpopulation of tumorigenic, aggressive, and
radioresistant cells, holds therapeutic promise. However, the effects of the microRNA miR …

LncRNA-XIST interacts with miR-29c to modulate the chemoresistance of glioma cell to TMZ through DNA mismatch repair pathway

P Du, H Zhao, R Peng, Q Liu, J Yuan, G Peng… - Bioscience …, 2017 - portlandpress.com
Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy.
However, growing resistance to TMZ remains a major challenge for clinicians. Recent …

Radiotherapy resistance: identifying universal biomarkers for various human cancers

I Larionova, M Rakina, E Ivanyuk, Y Trushchuk… - Journal of cancer …, 2022 - Springer
Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers,
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …

miR‐24‐3p promotes cell migration and proliferation in lung cancer by targeting SOX7

L Yan, J Ma, Y Zhu, J Zan, Z Wang… - Journal of cellular …, 2018 - Wiley Online Library
Lung cancer (LC) is one of the leading causes of cancer‐related death in the world. miR‐24‐
3p plays critical roles in many cancer types, including LC. In this study, we first investigated …

The potential role of miR‐29 in health and cancer diagnosis, prognosis, and therapy

M Alizadeh, A Safarzadeh… - Journal of cellular …, 2019 - Wiley Online Library
Abstract miR‐29 family is one of the small noncoding RNAs and has a very important role in
many physiologic and pathologic functions through regulating the target genes that play …