Recombinant viruses are the workhorse of modern neuroscience. Whether one would like to
understand a neuron's morphology, natural activity patterns, molecular composition …

In the past decade since kisspeptin/neurokinin B/dynorphin (KNDy) cells were first identified
in the mammalian hypothalamus, a plethora of new research has emerged adding insights …

Social behaviors are crucial to all mammals. Although the prelimbic cortex (PL, part of
medial prefrontal cortex) has been implicated in social behavior, it is not clear which …

Targeting genes to specific neuronal or glial cell types is valuable for both understanding
and repairing brain circuits. Adeno-associated viruses (AAVs) are frequently used for gene …

Hunger, driven by negative energy balance, elicits the search for and consumption of food.
While this response is in part mediated by neurons in the hypothalamus, the role of specific …

The striatal dopamine system has long been studied in the context of reward learning,
motivation, and movement. Given the prominent role dopamine plays in a variety of adaptive …

Food intake and body weight are tightly regulated by neurons within specific brain regions,
including the brainstem, where acute activation of dorsal raphe nucleus (DRN) …

Although microglial activation is widely found in amyotrophic lateral sclerosis (ALS) and
frontotemporal dementia (FTD), the underlying mechanism (s) are poorly understood. Here …

Homeostatic control of core body temperature is essential for survival. Temperature is
sensed by specific neurons, in turn eliciting both behavioral (ie, locomotion) and physiologic …

Chronic stress is a major risk factor for psychiatric disorders, including depression. Although
depression is a highly heterogeneous syndrome, it remains unclear how chronic stress …