The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …

Bladder cancer is a highly prevalent disease and is associated with substantial morbidity,
mortality and cost. Environmental or occupational exposures to carcinogens, especially …

Biological sex, being female or male, broadly influences diverse immune phenotypes,
including immune responses to diseases at mucosal surfaces. Sex hormones, sex …

A gender discrepancy exists in the incidence of both urothelial and kidney carcinomas, with
more men presenting with these cancers than women. Men have a threefold greater risk of …

Androgen-deprivation therapy (ADT) via targeting androgens/androgen receptor (AR)
signals may suppress cell proliferation in both prostate cancer (PCa) and bladder cancer …

Emerging preclinical findings have indicated that steroid hormone receptor signaling plays
an important role in bladder cancer outgrowth. In particular, androgen-mediated androgen …

Bladder cancer (BC) is a complex and highly heterogeneous stem cell disease associated
with high morbidity and mortality rates if it is not treated properly. Early diagnosis with …

While B cells in the tumor microenvironment may play important roles in cancer progression,
their impacts on the bladder cancer (BCa) metastasis remain unclear. Here we found from …

Little is known about biological significance of ELK1, a transcriptional factor that activates
downstream targets including c-fos proto-oncogene, in bladder cancer. Recent preclinical …

Bladder cancer is the ninth most common cancer worldwide with a striking sex-based
difference in incidence. Emerging evidence indicates that the androgen receptor (AR) might …