Regulation of intestinal lipid metabolism: current concepts and relevance to disease
Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …
[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis
MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
Lipid nanoparticles: Different preparation techniques, characterization, hurdles, and strategies for the production of solid lipid nanoparticles and nanostructured lipid …
P Ganesan, D Narayanasamy - Sustainable Chemistry and Pharmacy, 2017 - Elsevier
The bioavailability of an orally administered drug primarily depends on its solubility in the
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …
Strategies to address low drug solubility in discovery and development
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …
therefore, to variability in clinical response. Despite significant efforts to “design in” …
[图书][B] Principles of animal nutrition
G Wu - 2017 - taylorfrancis.com
Animals are biological transformers of dietary matter and energy to produce high-quality
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …
foods and wools for human consumption and use. Mammals, birds, fish, and shrimp require …
[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …
Intestinal lipid absorption and lipoprotein formation
MM Hussain - Current opinion in lipidology, 2014 - journals.lww.com
Triglycerides are exclusively transported with chylomicrons and this process is critically
dependent on MTP. In addition to chylomicrons, absorption of phospholipids, free …
dependent on MTP. In addition to chylomicrons, absorption of phospholipids, free …
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
Highly potent, but poorly water-soluble, drug candidates are common outcomes of
contemporary drug discovery programmes and present a number of challenges to drug …
contemporary drug discovery programmes and present a number of challenges to drug …
Intestinal lipid absorption
J Iqbal, MM Hussain - American Journal of Physiology …, 2009 - journals.physiology.org
Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has
advanced considerably. Researchers have identified several new mechanisms by which …
advanced considerably. Researchers have identified several new mechanisms by which …
DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
TO Eichmann, A Lass - Cellular and Molecular Life Sciences, 2015 - Springer
The neutral lipids diacylglycerols (DAGs) are involved in a plethora of metabolic pathways.
They function as components of cellular membranes, as building blocks for glycero …
They function as components of cellular membranes, as building blocks for glycero …