Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

Biological systems use proteins as scaffolds to harbor catalytic metal centers responsible for
the assimilatory and energy pathways that make life possible. Therefore, metal homeostasis …

It is well established that both, the deficiency and possible overload of mineral
micronutrients have adverse health effects. It is also generally accepted that non-essential …

Tetrathiomolybdate (TM) is an orally active agent for treatment of disorders of copper
metabolism. Here we describe how TM inhibits proteins that regulate copper physiology …

A ferrocene unit is introduced into the salicylaldehyde Rhodamine 6G hydrazone with an
alkynyl group to constitute a new chemosensor, R6G-FC, for specifically sensing Cu2+ over …

The central role of the prion protein (PrP) in a family of fatal neurodegenerate diseases has
garnered considerable research interest over the past two decades. Moreover, the role of …

A new rhodamine-based dual sensor selectively detects Cu2+ and Fe3+. Complexation with
Fe3+ triggers the formation of a highly fluorescent ring-open form, while Cu2+ forms a …

Three water-soluble fluorophores are synthesized from 1, 3, 5-tris-(4′-iodophenyl)
benzene. The compound with salicylate groups exhibits a selective fluorescent quenching …

The development of an inorganic–organic hybrid probe to more accurately detect ions in
living systems is very challenging but highly desirable. Here we combined upconversion …

Abstract A new 1, 8-naphthalimide-based Schiff base compound, named as (Z)-2-butyl-6-
(((2-hydroxyphenyl) imino) methyl)-1H-benzo [de] isoquinoline-1, 3 (2H)-dione (BHBD), has …