Network structure of the master clock is important for its primary function

C Gu, J Li, J Zhou, H Yang, J Rohling - Frontiers in Physiology, 2021 - frontiersin.org
A master clock located in the suprachiasmatic nucleus (SCN) regulates the circadian rhythm
of physiological and behavioral activities in mammals. The SCN has two main functions in …

[HTML][HTML] Heterogeneity of neuronal properties determines the collective behavior of the neurons in the suprachiasmatic nucleus

C Gu, P Wang, T Weng, H Yang… - Mathematical Biosciences …, 2019 - aimspress.com
Circadian rhythms have been observed in behavioral and physiological activities of living
things exposed to the natural 24 h light-darkness cycle. Interestingly, even under constant …

The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus

C Gu, A Ramkisoensing, Z Liu… - Journal of biological …, 2014 - journals.sagepub.com
In mammals, the central clock in the suprachiasmatic nucleus (SCN) controls physiological
and behavioral circadian rhythms and is entrained to the external light-dark cycle. The ability …

Entrainment maps: A new tool for understanding properties of circadian oscillator models

CO Diekman, A Bose - Journal of Biological Rhythms, 2016 - journals.sagepub.com
Circadian oscillators found across a variety of species are subject to periodic external light-
dark forcing. Entrainment to light-dark cycles enables the circadian system to align biological …

Motif structure for the four subgroups within the suprachiasmatic nuclei affects its entrainment ability

W Zheng, C Gu, H Yang, JHT Rohling - Physical Review E, 2022 - APS
Circadian rhythms of physiological and behavioral activities are regulated by a central clock.
This clock is located in the bilaterally symmetrical suprachiasmatic nucleus (SCN) of …

Coherency of circadian rhythms in the SCN is governed by the interplay of two coupling factors

IT Tokuda, D Ono, S Honma, KI Honma… - PLoS computational …, 2018 - journals.plos.org
Circadian clocks are autonomous oscillators driving daily rhythms in physiology and
behavior. In mammals, a network of coupled neurons in the suprachiasmatic nucleus (SCN) …

Impact of dispersed coupling strength on the free running periods of circadian rhythms

C Gu, JHT Rohling, X Liang, H Yang - Physical Review E, 2016 - APS
The dominant endogenous clock, named the suprachiasmatic nucleus (SCN), regulates
circadian rhythms of behavioral and physiological activity in mammals. One of the main …

The synchronization of neuronal oscillators determined by the directed network structure of the suprachiasmatic nucleus under different photoperiods

C Gu, M Tang, H Yang - Scientific Reports, 2016 - nature.com
The main function of the principal clock located in the suprachiasmatic nucleus (SCN) of
mammals is synchronizing the body rhythms to the 24 h light-dark cycle. Additionally, the …

A modeling approach shows the effects of different light–dark schemes on the entrainment ability of the suprachiasmatic nucleus

W Zheng, C Gu, H Yang, JHT Rohling - Nonlinear Dynamics, 2023 - Springer
In mammals, an endogenous clock located in the suprachiasmatic nucleus (SCN),
synchronizes physiological and biological rhythms to the environmental light–dark cycle. In …

Heterogeneity induces rhythms of weakly coupled circadian neurons

C Gu, X Liang, H Yang, JHT Rohling - Scientific reports, 2016 - nature.com
The main clock located in the suprachiasmatic nucleus (SCN) regulates circadian rhythms in
mammals. The SCN is composed of approximately twenty thousand heterogeneous self …