Increasing plant resistance to biotic and abiotic stresses may help to address global food
insecurity. We review small RNA (sRNA) research and consider the potential of sRNA-based …

Cultured cancer cells frequently rely on the consumption of glutamine and its subsequent
hydrolysis by glutaminase (GLS). However, this metabolic addiction can be lost in the …

Reduced activity of the enzymes encoded by PHGDH, PSAT1, and PSPH causes a set of
ultrarare, autosomal recessive diseases known as serine biosynthesis defects. These …

The mitochondrial enzyme fumarylacetoacetate hydrolase domain‐containing protein 1
(FAHD1) was identified to be upregulated in breast cancer tissues. Here, we show that …

Amoebiasis, a widespread disease caused by the protozoan parasite Entamoeba histolytica,
poses challenges due to the adverse effects of existing antiamoebic drugs and rising drug …

Vitamin B 6 plays a crucial role in cellular metabolism and stress response, making it an
essential component for growth in all known organisms. However, achieving efficient …

Lung cancer is the leading cause of cancer-related death. Intriguingly, males with non-small
cell lung cancer (NSCLC) have a higher mortality rate than females. Here, we investigated …

Background Pathogenic variants in PHGDH, PSAT1, and PSPH cause a set of rare,
autosomal recessive diseases known as serine biosynthesis defects. Serine biosynthesis …

Advancements in high-throughput sequencing technologies have accelerated the discovery
of human genetic variation. However, leveraging genomic information for precision medicine …

Many human diseases show sex differences in incidence, age of onset, and outcome,
including autoimmune diseases, neurological diseases, psychiatric disorders …