Liver pathologies (fibrosis, cirrhosis, alcoholic, non-alcoholic diseases and hepatocellular
carcinoma) represent one of the most common causes of death worldwide. A number of …

Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have
previously established a zebrafish model of diet-induced obesity (DIO zebrafish) by …

Nonalcoholic fatty liver disease (NAFLD) and its evolution to inflammatory steatohepatitis
(NASH) are the most common causes of chronic liver damage and transplantation that are …

The mitochondrial citrate carrier (CIC) is a member of the mitochondrial carrier family and is
responsible for the transit of tricarboxylates and dicarboxylates across the inner membrane …

Non-alcoholic fatty liver disease (NAFLD) pathogenesis remains poorly understood due to
the complex metabolic and inflammatory changes in the liver. This study aimed to elucidate …

In sepsis, limited food intake and increased energy expenditure induce a starvation
response, which is compromised by a quick decline in the expression of hepatic PPARα, a …

The metabolic syndrome has been associated with an alteration of intestinal microbiota,
which can be considered as a target for the management of these patients. Phenolic extracts …

Persistent inflammatory environment and abnormal macrophage activation are
characteristics of chronic diabetic wounds. Here, we attempted to characterize the …

Background and Purpose The ω‐3 polyunsaturated fatty acids (PUFAs) mediate protective
effects on several metabolic disorders. However, the functions of their metabolites in the …

Reduced expression of the Indy (“I am Not Dead, Yet”) gene in lower organisms promotes
longevity in a manner akin to caloric restriction. Deletion of the mammalian homolog of Indy …