Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

Ferroptosis is a kind of regulated cell death (RCD) caused by the redox state disorder of
intracellular microenvironment controlled by glutathione (GSH) peroxidase 4 (GPX4), which …

Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …

Background & Aims Single-cell transcriptomics offer unprecedented resolution of tissue
function at the cellular level, yet studies analyzing healthy adult human small intestine and …

Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell
death characterized by iron-dependence and the accumulation of lipid peroxidation that …

Dihydroartemisinin (DHA) has been shown to be capable of inhibiting cancer growth,
whereas it remains largely elusive that the underlying molecular mechanism of DHA …

Metals such as iron, manganese, copper, and zinc are recognized as essential trace
elements. These trace metals play critical roles in development, growth, and metabolism …

Iron is vital for many physiological functions, including energy production, and dysregulated
iron homeostasis underlies a number of pathologies. Ferroptosis is a recently recognized …

Obesity is a risk factor for several comorbidities and complications, including iron deficiency
anemia. Iron deficiency anemia is a serious global public health problem, with a worldwide …

Hereditary hemochromatosis (HH) is one of the most common genetic disorders among
persons of northern European descent. There have been recent advances in the diagnosis …