Mitochondrial mutations and genetic factors determining NAFLD risk

SA Dabravolski, EE Bezsonov, MS Baig… - International journal of …, 2021 - mdpi.com
NAFLD (non-alcoholic fatty liver disease) is a widespread liver disease that is often linked
with other life-threatening ailments (metabolic syndrome, insulin resistance, diabetes …

Exploring the role of genetic variations in NAFLD: implications for disease pathogenesis and precision medicine approaches

SK Mahmoudi, S Tarzemani, T Aghajanzadeh… - European Journal of …, 2024 - Springer
Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver
diseases, affecting more than one-quarter of people worldwide. Hepatic steatosis can …

Pro-and anti-inflammatory cytokines are the game-changers in childhood obesity-associated metabolic disorders (diabetes and non-alcoholic fatty liver diseases)

A Ullah, RK Singla, Z Batool, D Cao, B Shen - Reviews in Endocrine and …, 2024 - Springer
Childhood obesity is a chronic inflammatory epidemic that affects children worldwide.
Obesity affects approximately 1 in 5 children worldwide. Obesity in children can worsen …

Immunotherapy resumption/rechallenge in melanoma patients after toxicity: do we have another chance?

S España Fernandez, C Sun, C Solé-Blanch, A Boada… - Pharmaceutics, 2023 - mdpi.com
Introduction: Immune checkpoint inhibitors (ICIs) have radically changed the prognosis of
several neoplasias, among them metastatic melanoma. In the past decade, some of these …

非酒精性脂肪性肝病合并2 型糖尿病患者血清抵抗素和黄醇结合蛋白4 水平及其临床意义探讨

莫超艳, 杨有强, 钟嫄, 肖友雪 - 实用肝脏病杂志, 2022 - manu43.magtech.com.cn
目的探讨非酒精性脂肪性肝病(NAFLD) 合并2 型糖尿病(T2DM) 血清抵抗素和黄醇结合蛋白4
(RBP4) 水平变化及其临床意义. 方法2017 年10 月~ 2021 年1 月我院诊治的NAFLD 合并T2DM …

[HTML][HTML] Update on Non-Alcoholic Fatty Liver Disease-Associated Single Nucleotide Polymorphisms and Their Involvement in Liver Steatosis, Inflammation, and …

FD Astarini, N Ratnasari… - Iranian biomedical …, 2022 - ncbi.nlm.nih.gov
Genetic factors are involved in the development, progression, and severity of NAFLD.
Polymorphisms in genes regulating liver functions may increase liver susceptibility to …

Research of the Association of IL-17A RS (2275913) Gene Polymorphism with Allergic Rhinitis Associated with Food Co-sensitization.

N DUSTBABAEVA, F IRSALIEVA… - International …, 2020 - search.ebscohost.com
The Thl7 cells are well known to participate in the pathogenesis of inflammatory allergic and
autoimmune diseases, and are characterized by the predominant synthesis of cytokines IL …

[HTML][HTML] Allelic, Genotypic, and Haplotypic Analysis of Cytokine IL17A, IL17F, and Toll-like Receptor TLR4 Gene Polymorphisms in Metabolic-Dysfunction-Associated …

SC Coste, O Hilda Orășan, A Cozma, V Negrean… - Life, 2024 - mdpi.com
(1) Background: Interleukin 17 (IL17) and toll-like receptor 4 (TLR4) elevate the risk of
metabolic and liver diseases.(2) Methods: This study's objective was to explore the …

ABCA1 基因多态性R219K 与帕金森症和阿尔兹海默症发病率的相关性研究.

亚拉盖, 梁琨, 陶娜拉, 刘燕 - Progress in Modern …, 2020 - search.ebscohost.com
摘要目的: 探讨与研究三磷酸腺苷结合盒转运体A1 (Adenosine triphosphate (ATP)-binding
cassette transporter A1) 基因多态性R219K 与帕金森症(Parkinson disease, PD) …

[PDF][PDF] 伴有ABCA1 基因突变的青年代谢相关脂肪性肝硬化1 例报道

周丽丽, 施漪雯, 范建高, 孙超 - 实用肝脏病杂志, 2024 - manu43.magtech.com.cn
长期营养过剩导致的慢性代谢应激性肝损伤, 其不良结局为肝硬化, 肝细胞癌和肝功能衰竭[1, 2].
本文报道1 例28 岁年轻男性在腹腔镜下胆囊切除术时发现肝硬化改变, 遂在我院经基因检测和 …