▪ Abstract Complex II is the only membrane-bound component of the Krebs cycle and in
addition functions as a member of the electron transport chain in mitochondria and in many …

Mitochondrial complex II is traditionally studied for its participation in two key respiratory
processes: the electron transport chain and the Krebs cycle. There is now a rich body of …

Human complex II is a key protein complex that links two essential energy-producing
processes: the tricarboxylic acid cycle and oxidative phosphorylation. Deficiencies due to …

Derivatives of Escherichia coli C were engineered to produce primarily succinate or malate
in mineral salts media using simple fermentations (anaerobic stirred batch with pH control) …

Tetrahymena thermophila, a classic ciliate model organism, has been shown to possess
tubular mitochondrial cristae and highly divergent electron transport chain involving four …

The transfer of electrons and protons between membrane-bound respiratory complexes is
facilitated by lipid-soluble redox-active quinone molecules (Q). This work presents a …

We report three new structures of mitochondrial respiratory Complex II (succinate
ubiquinone oxidoreductase, EC 1.3. 5.1) at up to 2.1 Å resolution, with various inhibitors …

Enzymes in the mitochondrial respiratory chain are involved in various physiological events
in addition to their essential role in the production of ATP by oxidative phosphorylation. The …

Although the human gut microbiome plays a prominent role in xenobiotic transformation,
most of the genes and enzymes responsible for this metabolism are unknown. Recently, we …

During evolution, many new proteins have been formed by the process of gene duplication
and combination. The genes involved in this process usually code for whole domains. Small …