Nanotechnology based drug delivery system: Current strategies and emerging therapeutic potential for medical science

T Sahu, YK Ratre, S Chauhan, L Bhaskar… - Journal of Drug Delivery …, 2021 - Elsevier
Nanotechnology or Nano medicine has been identified as the dominant and most
commercially invented technology that aims to improve the quality of health care strategies …

[HTML][HTML] ABC transporters affects tumor immune microenvironment to regulate cancer immunotherapy and multidrug resistance

J Fan, KKW To, ZS Chen, L Fu - Drug Resistance Updates, 2023 - Elsevier
Multidrug resistance (MDR) is the phenomenon in which cancer cells simultaneously
develop resistance to a broad spectrum of structurally and mechanistically unrelated drugs …

Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation

Y Luo, S Zheng, Q Wu, J Wu, R Zhou, C Wang, Z Wu… - Autophagy, 2021 - Taylor & Francis
Chemotherapy is currently the main treatment for unresectable or advanced postoperative
gastric cancers. However, its efficacy is negatively affected by the occurrence of …

The role of autophagy in gastric cancer chemoresistance: friend or foe?

JL Xu, L Yuan, YC Tang, ZY Xu, HD Xu… - Frontiers in Cell and …, 2020 - frontiersin.org
Gastric cancer is the third most common cause of cancer-related death worldwide. Drug
resistance is the main inevitable and vital factor leading to a low 5-year survival rate for …

Helicobacter pylori promotes gastric cancer progression through the tumor microenvironment

L Zhu, Y Huang, H Li, S Shao - Applied Microbiology and Biotechnology, 2022 - Springer
Gastric cancer (GC) is a leading type of cancer. Although immunotherapy has yielded
important recent progress in the treatment of GC, the prognosis remains poor due to drug …

Metallothionein isoforms as double agents–their roles in carcinogenesis, cancer progression and chemoresistance

MAM Rodrigo, AMJ Jimemez, Y Haddad… - Drug Resistance …, 2020 - Elsevier
Metallothioneins (MTs) are small cysteine-rich intracellular proteins with four major isoforms
identified in mammals, designated MT-1 through MT-4. The best known biological functions …

MAP kinases pathways in gastric cancer

L Magnelli, N Schiavone, F Staderini… - International Journal of …, 2020 - mdpi.com
Gastric cancer (GC) is turning out today to be one of the most important welfare issues for
both Asian and European countries. Indeed, while the vast majority of the disease burden is …

Molecular bases of mechanisms accounting for drug resistance in gastric adenocarcinoma

JJG Marin, L Perez-Silva, RIR Macias, M Asensio… - Cancers, 2020 - mdpi.com
Gastric adenocarcinoma (GAC) is the most common histological type of gastric cancer, the
fifth according to the frequency and the third among the deadliest cancers. GAC high …

[HTML][HTML] Roles of S100 family members in drug resistance in tumors: Status and prospects

X Hua, H Zhang, J Jia, S Chen, Y Sun, X Zhu - Biomedicine & …, 2020 - Elsevier
Chemotherapy and targeted therapy can significantly improve survival rates in cancer, but
multiple drug resistance (MDR) limits the efficacy of these approaches. Understanding the …

A SOX2 reporter system identifies gastric cancer stem-like cells sensitive to monensin

D Pádua, R Barros, A Luísa Amaral, P Mesquita… - Cancers, 2020 - mdpi.com
Gastric cancer remains a serious health burden with few therapeutic options. Therefore, the
recognition of cancer stem cells (CSCs) as seeds of the tumorigenic process makes them a …