Regulation of IGF-1 signaling by microRNAs

HJ Jung, Y Suh - Frontiers in genetics, 2015 - frontiersin.org
The insulin-like growth factor 1 (IGF-1) signaling pathway regulates critical biological
processes including development, homeostasis, and aging. Dysregulation of this pathway …

Psoriasis and psoriatic arthritis: clinical features and disease mechanisms

WA Myers, AB Gottlieb, P Mease - Clinics in dermatology, 2006 - Elsevier
Psoriasis is a chronic skin disorder affecting approximately 1% to 3% of the world's
population. A considerable proportion of patients with psoriasis will develop a form of …

Development of an in vitro psoriatic skin model by tissue engineering

J Jean, M Lapointe, J Soucy, R Pouliot - Journal of dermatological science, 2009 - Elsevier
BACKGROUND: Psoriasis is a chronic skin disease characterized by a thickening and
disorganization of the skin's protective barrier. OBJECTIVES: This study aims to develop and …

MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R

G Lerman, C Avivi, C Mardoukh, A Barzilai, A Tessone… - PloS one, 2011 - journals.plos.org
Background Psoriasis is a complex disease at the cellular, genomic and genetic levels. The
role of microRNAs in skin development was shown in a keratinocyte-specific Dicer knockout …

Psoriasis clinical implications and treatment: a review

AS Raut, RH Prabhu… - Critical Reviews™ in …, 2013 - dl.begellhouse.com
Psoriasis is a common skin disorder affecting the population worldwide. It is a T-cell
mediated autoimmune disorder leading to keratinocyte hyperproliferation. Psoriasis has …

From the Medical Board of the National Psoriasis Foundation: monitoring and vaccinations in patients treated with biologics for psoriasis

M Lebwohl, J Bagel, JM Gelfand, D Gladman… - Journal of the American …, 2008 - Elsevier
BACKGROUND: Biologics are widely used in the treatment of psoriasis and psoriatic
arthritis. OBJECTIVE: Our aim was to arrive at a consensus on the kind of monitoring and the …

Quality of life in patients with psoriasis and psoriasis arthritis with a special focus on stigmatization experience

G Schmid-Ott, S Schallmayer, IT Calliess - Clinics in dermatology, 2007 - Elsevier
Negative impact of psoriasis and psoriasis arthritis on quality of life is a central consequence
of these diseases. Feelings of stigmatization might, for example, already emerge with only …

Cysteine cathepsin S as an immunomodulatory target: present and future trends

S Gupta, RK Singh, S Dastidar… - Expert opinion on …, 2008 - Taylor & Francis
Objective: Antigen presentation is the key to immune response. Cathepsin S plays a major
role in the degradation of the invariant peptide chain associated with the major …

Anti-inflammatory, Immunomodulatory and DFT Evaluation of the Reactivity Indexes of Phytochemicals Isolated from Harungana madagascariensis

FC Asogwa, CG Apebende, GW Ugodi, P Ebo, H Louis… - Chemistry Africa, 2023 - Springer
The anti-inflammatory and immunomodulatory properties of Harungana madagascariensis
(HM) leaf extract was experimentally investigated and the electronic structure property of the …

Emotion regulation in patients with psoriasis: Correlates of disability, clinical dimensions, and psychopathology symptoms

V Almeida, S Taveira, M Teixeira, I Almeida… - International journal of …, 2017 - Springer
Purpose There are known connections between emotions and psoriasis; however, we have
not established a clear pathway for this association. This study aimed to explore correlates …