Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …

Beyond fuelling cellular activities with building blocks and energy, metabolism also
integrates environmental conditions into intracellular signals. The underlying regulatory …

The bacterial phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS)
carries out both catalytic and regulatory functions. It catalyzes the transport and …

Most bacteria can selectively use substrates from a mixture of different carbon sources. The
presence of preferred carbon sources prevents the expression, and often also the activity, of …

The phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS) is found
only in bacteria, where it catalyzes the transport and phosphorylation of numerous …

To succeed, many cells must alternate between life-styles that permit rapid growth in the
presence of abundant nutrients and ones that enhance survival in the absence of those …

Metabolically versatile free-living bacteria have global regulation systems that allow cells to
selectively assimilate a preferred compound among a mixture of several potential carbon …

Bacteria live in environments that are subject to rapid changes in the availability of the
nutrients that are necessary to provide energy and biosynthetic intermediates for the …

The remarkable ability of bacteria to adapt efficiently to a wide range of nutritional
environments reflects their use of overlapping regulatory systems that link gene expression …

▪ Abstract The gram-positive bacterium Bacillus subtilis is capable of using numerous
carbohydrates as single sources of carbon and energy. In this review, we discuss the …