Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians

D Moris, M Palta, C Kim, PJ Allen… - CA: a cancer journal …, 2023 - Wiley Online Library
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver tumor and
remains a fatal malignancy in the majority of patients. Approximately 20%–30% of patients …

Current surgical management of peri-hilar and intra-hepatic cholangiocarcinoma

A Lauterio, R De Carlis, L Centonze, V Buscemi… - Cancers, 2021 - mdpi.com
Simple Summary The treatment of peri-hilar (h-CCA) and intrahepatic (i-CCA)
cholangiocarcinoma is an evolving field in hepato-pancreato-biliary surgery. Continuous …

Genetic determinants of outcome in intrahepatic cholangiocarcinoma

T Boerner, E Drill, LM Pak, B Nguyen, CS Sigel… - …, 2021 - Wiley Online Library
Background and Aim Genetic alterations in intrahepatic cholangiocarcinoma (iCCA) are
increasingly well characterized, but their impact on outcome and prognosis remains …

Treatment of Intrahepatic Cholangiocarcinoma—A Multidisciplinary Approach

F Krenzien, N Nevermann, A Krombholz, C Benzing… - Cancers, 2022 - mdpi.com
Simple Summary This review discusses multimodality treatment strategies for intrahepatic
cholangiocarcinoma (iCC). Surgical resection remains the only potentially curative …

[HTML][HTML] Neoadjuvant therapy for cholangiocarcinoma: A comprehensive literature review

A Rizzo, G Brandi - Cancer Treatment and Research Communications, 2021 - Elsevier
Biliary tract cancers (BTCs) comprise a heterogenous group of aggressive and rare
malignancies arising in the bile duct outside or within the liver. BTCs include …

[HTML][HTML] Neoadjuvant treatment strategies for intrahepatic cholangiocarcinoma

C Akateh, AM Ejaz, TM Pawlik… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver malignancy
and is increasing in incidence. Long-term outcomes are optimized when patients undergo …

EASL-ILCA Clinical Practice Guidelines on the management of intrahepatic cholangiocarcinoma

D Alvaro, GJ Gores, J Walicki, C Hassan… - Journal of …, 2023 - Elsevier
Intrahepatic cholangiocarcinoma (iCCA) develops inside the liver, between bile ductules
and the second-order bile ducts. It is the second most frequent primary liver cancer after …

Systematic review and meta-analysis of prognostic factors for early recurrence in intrahepatic cholangiocarcinoma after curative-intent resection

WJ Choi, PJ Williams, MPAW Claasen, T Ivanics… - Annals of surgical …, 2022 - Springer
Background Recurrence rates of intrahepatic cholangiocarcinoma (iCCA) after curative
hepatectomy are as high as 50% to 70%, and about half of these recurrences occur within 2 …

Neoadjuvant chemotherapy for intrahepatic cholangiocarcinoma: a propensity score survival analysis supporting use in patients with high-risk disease

O Utuama, JB Permuth, G Dagne… - Annals of Surgical …, 2021 - Springer
Background Upfront surgery is the current standard for resectable intrahepatic
cholangiocarcinoma (ICC) despite high treatment failure with this approach. We sought to …

Current perspectives on the surgical management of perihilar cholangiocarcinoma

DB Hewitt, ZJ Brown, TM Pawlik - Cancers, 2022 - mdpi.com
Simple Summary Perihilar cholangiocarcinoma is a rare disease with generally poor
outcomes. Complete surgical resection remains the only chance at long-term survival …