Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …

Integrons recombine gene arrays and favor the spread of antibiotic resistance. Their broader
roles in bacterial adaptation remain mysterious, partly due to lack of computational tools. We …

Class 1 integrons are widespread genetic elements that allow bacteria to capture and
express gene cassettes that are usually promoterless. These integrons play a major role in …

Bacterial resistance to β-lactams may rely on acquired β-lactamases encoded by class 1
integron-borne genes. Rearrangement of integron cassette arrays is mediated by the …

Background Integrons are found in hundreds of environmental bacterial species, but are
mainly known as the agents responsible for the capture and spread of antibiotic-resistance …

The integron is a bacterial recombination system that allows acquisition, stockpiling and
expression of cassettes carrying protein-coding sequences, and is responsible for the …

Integrons are genetic elements that store, express and exchange gene cassettes. These
elements are characterized by containing a gene that codes for an integrase (int I), a …

Recombination systems are widely used as bioengineering tools, but their sites have to be
highly similar to a consensus sequence or to each other. To develop a recombination …

Biologically functional DNA hairpins are found in archaea, prokaryotes and eukaryotes,
playing essential roles in various DNA transactions. However, during DNA replication …

By mobilizing small DNA units, integrons have a major function in the dissemination of
antibiotic resistance among bacteria. The acquisition of gene cassettes occurs by …