Taking phototherapeutics from concept to clinical launch

BM Vickerman, EM Zywot, TK Tarrant… - Nature Reviews …, 2021 - nature.com
More than four decades have passed since the first example of a light-activated (caged)
compound was described. In the intervening years, a large number of light-responsive …

Shining light on the head: photobiomodulation for brain disorders

MR Hamblin - BBA clinical, 2016 - Elsevier
Photobiomodulation (PBM) describes the use of red or near-infrared light to stimulate, heal,
regenerate, and protect tissue that has either been injured, is degenerating, or else is at risk …

Brain photobiomodulation therapy: a narrative review

F Salehpour, J Mahmoudi, F Kamari… - Molecular …, 2018 - Springer
Brain photobiomodulation (PBM) therapy using red to near-infrared (NIR) light is an
innovative treatment for a wide range of neurological and psychological conditions. Red/NIR …

Photobiomodulation for traumatic brain injury and stroke

MR Hamblin - Journal of neuroscience research, 2018 - Wiley Online Library
There is a notable lack of therapeutic alternatives for what is fast becoming a global
epidemic of traumatic brain injury (TBI). Photobiomodulation (PBM) employs red or near …

Deep optoacoustic localization microangiography of ischemic stroke in mice

XL Deán-Ben, J Robin, D Nozdriukhin, R Ni… - Nature …, 2023 - nature.com
Super-resolution optoacoustic imaging of microvascular structures deep in mammalian
tissues has so far been impeded by strong absorption from densely-packed red blood cells …

Non-invasive transcranial brain modulation for neurological disorders treatment: a narrative review

EA Mosilhy, EE Alshial, MM Eltaras, MMA Rahman… - Life Sciences, 2022 - Elsevier
Noninvasive brain stimulation/modulation is a rapidly emerging technique that has been
implemented in different clinical applications. The commonly noninvasive techniques used …

Penetration profiles of visible and near-infrared lasers and light-emitting diode light through the head tissues in animal and human species: a review of literature

F Salehpour, P Cassano, N Rouhi… - … , and laser surgery, 2019 - liebertpub.com
Background and objective: Photobiomodulation (PBM) therapy is a promising and
noninvasive approach to stimulate neuronal function and improve brain repair. The …

Photobiomodulation for the aging brain

F dos Santos Cardoso, F Gonzalez-Lima… - Ageing Research …, 2021 - Elsevier
Longevity is one of the great triumphs of humanity. Worldwide, the elderly is the fastest
growing segment of the population. As a consequence, the number of cases of age-related …

[HTML][HTML] Effects of prenatal photobiomodulation treatment on neonatal hypoxic ischemia in rat offspring

L Yang, Y Dong, C Wu, H Youngblood, Y Li, X Zong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Neonatal hypoxic-ischemic (HI) injury is a severe complication often leading to neonatal
death and long-term neurobehavioral deficits in children. Currently, the only treatment option …

Transcranial photobiomodulation with 1064-nm laser modulates brain electroencephalogram rhythms

X Wang, JP Dmochowski, L Zeng… - …, 2019 - spiedigitallibrary.org
Noninvasive transcranial photobiomodulation (tPBM) with a 1064-nm laser has been
reported to improve human performance on cognitive tasks as well as locally upregulate …