GPCRs make up the largest family of human membrane proteins and of drug targets. Recent
advances in GPCR pharmacology and crystallography have shed new light on signal …

The ESTHER database, dedicated to ESTerases and alpha/beta-Hydrolase Enzymes and
Relatives (https://bioweb. supagro. inra. fr/ESTHER/general? what= index), offers online …

Precision medicine and personalized health efforts propose leveraging complex molecular,
medical and family history, along with other types of personal data toward better life. We …

Biological databases are online libraries that contain structured information about living
organisms. These databases are indispensable research tools, as they provide convenient …

OMPdb (www. ompdb. org) was introduced as a database for β-barrel outer membrane
proteins from Gram-negative bacteria in 2011 and then included 69,354 entries classified …

Background: Analysis of the distribution of amino acid types found at equivalent positions in
multiple sequence alignments has found applications in human genetics, protein …

We describe a series of databases and tools that directly or indirectly support biomedical
research on macromolecules, with focus on their applicability in protein structure …

Organophosphates (OPs) are either found in nature or synthetized for use as pesticides,
flame retardants, neurotoxic warfare agents or drugs (cholinergic enhancers in Alzheimer's …

With ever-increasing amounts of sequence data available in both the primary literature and
sequence repositories, there is a bottleneck in annotating molecular function to a sequence …

Background: Analysis of the distribution of amino acid types found at equivalent positions in
multiple sequence alignments has found applications in human genetics, protein …