Molecular permeation through lipid membranes is a fundamental biological process that is
important for small neutral molecules and drug molecules. Precise characterization of free …

This is a review. Non-electrolytic compounds typically cross cell membranes by passive
diffusion. The rate of permeation is dependent on the chemical properties of the solute and …

Although the general mechanisms of lipid oxidation are known, the chemical steps through
which photosensitizers and light permeabilize lipid membranes are still poorly understood …

Despite intense study over many years, the mechanisms by which water and small
nonelectrolytes cross lipid bilayers remain unclear. While prior studies of permeability …

Cholesterol plays an important role in maintaining the correct fluidity and rigidity of the
plasma membrane of all animal cells, and hence, it is present in concentrations ranging from …

The transmembrane permeation of eight small (molecular weight< 100) organic molecules
across a phospholipid bilayer is investigated by multiscale molecular dynamics simulation …

Using the potential of mean constrained force method, molecular dynamics simulations with
atomistic details were performed to examine the partitioning and nature of interactions of two …

Rapid development of computer power during the last decade has made molecular
simulations of lipid bilayers feasible for many research groups, which, together with the …

The passive transport of molecules through a cell membrane relies on thermal motions of
the lipids. However, the nature of transmembrane transport and the precise mechanism …

Liposomes are lipid vesicles made of one or multiple lipid bilayers surrounding an internal
aqueous core. They are broadly employed as models to study membrane structure and …