Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches
In patients with Parkinson's disease, heterogeneous cholinergic system changes can occur
in different brain regions. These changes correlate with a range of clinical features, both …
in different brain regions. These changes correlate with a range of clinical features, both …
Neuroprosthetics: from sensorimotor to cognitive disorders
Neuroprosthetics is a multidisciplinary field at the interface between neurosciences and
biomedical engineering, which aims at replacing or modulating parts of the nervous system …
biomedical engineering, which aims at replacing or modulating parts of the nervous system …
Sex differences in dementia with Lewy bodies: focused review of available evidence and future directions
SY Chiu, KA Wyman-Chick, TJ Ferman… - Parkinsonism & related …, 2023 - Elsevier
In this review, we summarize the current knowledge on sex differences in dementia with
Lewy bodies (DLB) relating to epidemiology, clinical features, neuropathology, biomarkers …
Lewy bodies (DLB) relating to epidemiology, clinical features, neuropathology, biomarkers …
[HTML][HTML] Probing responses to deep brain stimulation with functional magnetic resonance imaging
Background Deep brain stimulation (DBS) is an established treatment for certain movement
disorders and has additionally shown promise for various psychiatric, cognitive, and seizure …
disorders and has additionally shown promise for various psychiatric, cognitive, and seizure …
Structural (dys) connectivity associates with cholinergic cell density in Alzheimer's disease
CP Lin, I Frigerio, BDC Boon, Z Zhou, AJM Rozemuller… - Brain, 2022 - academic.oup.com
Cognitive deficits in Alzheimer's disease, specifically amnestic (memory dominant) deficits,
are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus …
are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus …
Deep brain stimulation initiative: toward innovative technology, new disease indications, and approaches to current and future clinical challenges in neuromodulation …
Deep brain stimulation (DBS) is one of the most important clinical therapies for neurological
disorders. DBS also has great potential to become a great tool for clinical neuroscience …
disorders. DBS also has great potential to become a great tool for clinical neuroscience …
Advances in DBS technology and novel applications: focus on movement disorders
Abstract Purpose of Review Deep brain stimulation (DBS) is an established treatment in
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …
Alzheimer's disease: An evolving understanding of noradrenergic involvement and the promising future of electroceutical therapies
Alzheimer's disease (AD) poses a significant global health concern over the next several
decades. Multiple hypotheses have been put forth that attempt to explain the underlying …
decades. Multiple hypotheses have been put forth that attempt to explain the underlying …
Cortical connectivity of the nucleus basalis of Meynert in Parkinson's disease and Lewy body dementias
Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB) are related
conditions that are associated with cholinergic system dysfunction. Dysfunction of the …
conditions that are associated with cholinergic system dysfunction. Dysfunction of the …
Deep brain stimulation in Parkinson's disease: state of the art and future perspectives
For more than 30 years, Deep Brain Stimulation (DBS) has been a therapeutic option for
Parkinson's disease (PD) treatment. However, this therapy is still underutilized mainly due to …
Parkinson's disease (PD) treatment. However, this therapy is still underutilized mainly due to …