Stressors of emerging concern in deep-sea environments: microplastics, pharmaceuticals, personal care products and deep-sea mining
Although most deep-sea areas are remote in comparison to coastal zones, a growing body
of literature indicates that many sensitive ecosystems could be under increased stress from …
of literature indicates that many sensitive ecosystems could be under increased stress from …
Freshwater crustacean exposed to active pharmaceutical ingredients: ecotoxicological effects and mechanisms
J Guo, J Ren, C Chang, Q Duan, J Li… - … Science and Pollution …, 2023 - Springer
Concerns over the ecotoxicological effects of active pharmaceutical ingredients (APIs) on
aquatic invertebrates have been raised in the last decade. While numerous studies have …
aquatic invertebrates have been raised in the last decade. While numerous studies have …
History of exposure to copper influences transgenerational gene expression responses in Daphnia magna
G Jeremias, AB Muñiz-González… - Epigenetics, 2024 - Taylor & Francis
The establishment of transgenerational effects following chemical exposure is a powerful
phenomenon, capable of modulating ecosystem health beyond exposure periods. This …
phenomenon, capable of modulating ecosystem health beyond exposure periods. This …
Biosynthesis of long-chain polyunsaturated fatty acids in marine gammarids: molecular cloning and functional characterisation of three fatty acyl elongases
Long-chain (C20–24) polyunsaturated fatty acids (LC-PUFAs) are essential nutrients that
are mostly produced in marine ecosystems. Previous studies suggested that gammarids …
are mostly produced in marine ecosystems. Previous studies suggested that gammarids …
Epigenetic biomarkers as tools for chemical hazard assessment: Gene expression profiling using the model Danio rerio
Recent reports raise the concern that exposure to several environmental chemicals may
induce persistent changes that go beyond the exposed organisms, being transferred to …
induce persistent changes that go beyond the exposed organisms, being transferred to …
Are fish populations at risk? Metformin disrupts zebrafish development and reproductive processes at chronic environmentally relevant concentrations
S Barros, N Alves, M Pinheiro, M Ribeiro… - Environmental …, 2022 - ACS Publications
The antidiabetic drug Metformin (MET), one of the most prevalent pharmaceuticals in the
environment, is currently detected in surface waters in the range of ng/L to low μg/L. As …
environment, is currently detected in surface waters in the range of ng/L to low μg/L. As …
Neuroendocrine pathways at risk? Simvastatin induces inter and transgenerational disruption in the keystone amphipod Gammarus locusta
The primary focus of environmental toxicological studies is to address the direct effects of
chemicals on exposed organisms (parental generation–F0), mostly overlooking effects on …
chemicals on exposed organisms (parental generation–F0), mostly overlooking effects on …
[HTML][HTML] The anti-lipidemic drug simvastatin modifies epigenetic biomarkers in the amphipod Gammarus locusta
The adverse effects of certain environmental chemicals have been recently associated with
the modulation of the epigenome. Although changes in the epigenetic signature have yet to …
the modulation of the epigenome. Although changes in the epigenetic signature have yet to …
[HTML][HTML] Transcriptomic data on the transgenerational exposure of the keystone amphipod Gammarus locusta to simvastatin
The use of transcriptomics data brings new insights and works as a powerful tool to explore
the molecular mode of action (MoA) of transgenerational inheritance effects of contaminants …
the molecular mode of action (MoA) of transgenerational inheritance effects of contaminants …
Using zebrafish embryo bioassays to identify chemicals modulating the regulation of the epigenome: a case study with simvastatin
T Torres, S Barros, T Neuparth, R Ruivo… - … Science and Pollution …, 2023 - Springer
Contaminants of emerging concern have been increasingly associated with the modulation
of the epigenome, leading to potentially inherited and persistent impacts on apical …
of the epigenome, leading to potentially inherited and persistent impacts on apical …